ANTITHROMBIN ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Rx (2014)

First approved in 2009

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 09:34:04 GMT 2025` Edited by `admin` on `Wed Apr 02 09:34:04 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	AWV6I5L6H2
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

ANTITHROMBIN ALFA

Official Name

English

antithrombin alfa [INN]

Preferred Name

English

ANTITHROMBIN ALFA [USAN]

Common Name

English

ANTITHROMBIN ALFA [EMA EPAR]

Common Name

English

ANTITHROMBIN ALFA [MART.]

Common Name

English

ATRYN

Brand Name

English

Antithrombin Alfa [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C263

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

FDA ORPHAN DRUG

246807

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

EMA ASSESSMENT REPORTS

ATRYN (AUTHORIZED: ANTITHROMBIN III DEFICIENCY)

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

FDA ORPHAN DRUG

118798

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

NDF-RT

N0000184170

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL1201554

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

INN

8429

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

FDA UNII

AWV6I5L6H2

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

SMS_ID

100000087989

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

CAS

84720-88-7

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

RXCUI

1427179

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

RxNorm

EVMPD

SUB22365

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

NDF-RT

N0000008556

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

Decreased Coagulation Factor Activity [PE]

NCI_THESAURUS

C82234

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

DRUG BANK

DB11166

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

UNIPROT

P01008

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

USAN

TT-126

Created by admin on Wed Apr 02 09:34:04 GMT 2025 , Edited by admin on Wed Apr 02 09:34:04 GMT 2025

PRIMARY

From	To
1_8	1_128
1_21	1_95
1_247	1_430

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_96
N	1_135
N	1_155
N	1_192

Related Record Type Details

ANTITHROMBIN (RECOMBINANT)

SUB_CONCEPT->SUBSTANCE

Related Record Type Details


					AWV6I5L6H2

ANTITHROMBIN ALFA

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_36]		S		DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL