Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C13H16N2O3 |
| Molecular Weight | 248.2777 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)C(CN)C1=CNC2=CC=C(OC)C=C12
InChI
InChIKey=YFEDJMLMWJSRJJ-UHFFFAOYSA-N
InChI=1S/C13H16N2O3/c1-17-8-3-4-12-9(5-8)11(7-15-12)10(6-14)13(16)18-2/h3-5,7,10,15H,6,14H2,1-2H3
| Molecular Formula | C13H16N2O3 |
| Molecular Weight | 248.2777 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Indorenate (TR3369, INDO) is a serotonin-like compound with high affinity for 5- HT1A receptors and a lower affinity for 5-HT1C and 5-HT1B receptors. Indorenate possesses antihypertensive and anxiolytic activity in animal behaviour tests. Similar to other serotonin receptor agonists, Indorenate also has anorectic activity; this effect was blocked by the administration of the 5-HT2A/2C receptor antagonists cinanserin, cyproheptadine, metergoline and methysergide. A unpublished clinical trial confirmed its antihypertensive activity in men.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:51:10 UTC 2023
by
admin
on
Sat Dec 16 17:51:10 UTC 2023
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| Record UNII |
AV9L041QA4
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| Record Status |
Validated (UNII)
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| Record Version |
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Official Name | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C47794
Created by
admin on Sat Dec 16 17:51:10 UTC 2023 , Edited by admin on Sat Dec 16 17:51:10 UTC 2023
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| Code System | Code | Type | Description | ||
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C033600
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73758-06-2
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INDORENATE
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AV9L041QA4
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4929
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DTXSID2048400
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C83802
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71987
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SUB08185MIG
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100000083396
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CHEMBL414636
Created by
admin on Sat Dec 16 17:51:10 UTC 2023 , Edited by admin on Sat Dec 16 17:51:10 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
