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LUSPATERCEPT
AQK7UBA1LS
US Approved Rx (2019)
First approved in 2019
General
Record Details
Variant Concepts
1
Names
7
Classification
4
Identifiers
14
Subunits
2
Disulfide Links
16
Glycosylation
6
Relationships
1
Active Moiety
1
Characteristic Attributes
2
LUSPATERCEPT
AQK7UBA1LS
US Approved Rx (2019)
First approved in 2019
General
Approval Year
2019
334
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
AQK7UBA1LS
Record Status
Validated (UNII)
Record Version
27
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Related Record
Type
Related Record
Type
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Names
7
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entries
Name
Type
Language
Name
Type
Language
LUSPATERCEPT
Official Name
English
LUSPATERCEPT [MI]
Common Name
English
ACE-536
Code
English
LUSPATERCEPT [USAN]
Common Name
English
ACTIVIN RECEPTOR TYPE IIB (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN 107-AMINO ACID FRAGMENT) FUSION PROTEIN WITH GLYCYLGLYCYLGLYCINE FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN FC REGION 225-AMINO ACID C-TERMINAL FRAGMENT), DIMER
Common Name
English
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2
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Classification
4
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Positive
EU ORPHAN DRUG
Positive
Treatment of beta thalassaemia intermedia and major
EU-Orphan Drug
EU/3/14/1300
Designated
ORPHAN DRUG
Designated
Treatment of Alpha-thalassemia
FDA ORPHAN DRUG
837321
Pharmacologic Substance
Pharmacologic Substance
[C1909]
Biological Agent
NCI_THESAURUS
C307
Designated
ORPHAN DRUG
Designated
Treatment of myelofibrosis
FDA ORPHAN DRUG
718419
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Identifiers
14
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Code System
Code
Type
Description
Code System
Code
Type
Description
RXCUI
2262543
ALTERNATIVE
NCI_THESAURUS
C104012
PRIMARY
ChEMBL
CHEMBL3039545
PRIMARY
DRUG CENTRAL
5364
PRIMARY
CAS
1373715-00-4
PRIMARY
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Subunits
2
Subunit 0
>SUBUNIT_0
Subunit 1
>SUBUNIT_1
Disulfide Links
16
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From
To
From
To
1_5
1_35
1_25
1_53
1_60
1_79
1_66
1_78
1_80
1_85
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1
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Glycosylation
6
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_18
N
1_41
N
1_185
N
2_18
N
2_41
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
LUSPATERCEPT-AAMT
SUB_CONCEPT->SUBSTANCE
Amount:
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Active Moiety
1
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Related Record
Type
Details
Related Record
Type
Details
AQK7UBA1LS
LUSPATERCEPT
ACTIVE MOIETY
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Characteristic Attributes
2
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 76000 Da (average)
Molecular Formula
CHEMICAL
ESTIMATED
C3350H5064N906O1044S38
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