Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C3H5O3 |
| Molecular Weight | 89.07 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | -1 |
SHOW SMILES / InChI
SMILES
C[C@@H](O)C([O-])=O
InChI
InChIKey=JVTAAEKCZFNVCJ-UWTATZPHSA-M
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/p-1/t2-/m1/s1
| Molecular Formula | C3H6O3 |
| Molecular Weight | 90.0779 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Lactic acid, D- is a natural optical isomer of lactic acid. It is a poorly utilized isomer – 30 to 40% of the dose ingested is excreted in the urine. Lactic acid, D- is known to be harmful to human metabolism and it can result in acidosis and decalcification. D-lactic acidosis, also referred as D-lactate encephalopathy, has been reported in patients with short bowl syndrome. Lactic acid, D- is an interesting precursor for manufacturing heat-resistant polylactic acid (PLA) bioplastics which can be widely used, for example as packaging material, coatings, for textiles or in the automotive industry.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Fluorimetric assay of D-lactate. | 1992 Oct |
|
| Metabolic differences between attached and free-living marine bacteria: inadequacy of liquid cultures for describing in situ bacterial activity. | 2001 Jan 1 |
|
| Conversion of sodium lactate to lactic acid with water-splitting electrodialysis. | 2001 Jun |
|
| Extracellular carbonic anhydrase activity facilitates lactic acid transport in rat skeletal muscle fibres. | 2001 Mar 15 |
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| Enhanced inhibition of Listeria monocytogenes and salmonella enteritidis in meat by combinations of sodium lactate and diacetate. | 2001 May |
|
| Organic acids and their salts as dipping solutions to control listeria monocytogenes inoculated following processing of sliced pork bologna stored at 4 degrees C in vacuum packages. | 2001 Nov |
|
| Intragastric calcium infusions support flavor preference learning by calcium-deprived rats. | 2002 Aug |
|
| Control of Listeria monocytogenes with combined antimicrobials after postprocess contamination and extended storage of frankfurters at 4 degrees C in vacuum packages. | 2002 Feb |
|
| Effect of toothbrushing on the toxicity of casting alloys. | 2002 Jan |
|
| Process development and optimisation of lactic acid purification using electrodialysis. | 2002 Jul 3 |
|
| Automated measurements of antilisterial activities of lactate and diacetate in ready-to-eat meat. | 2002 May |
|
| Contraction-related factors affect the concentration of a kallidin-like peptide in rat muscle tissue. | 2002 Oct 1 |
|
| Second-generation mimics of ganglioside GM1 oligosaccharide: a three-dimensional view of their interactions with bacterial enterotoxins by NMR and computational methods. | 2002 Oct 18 |
|
| Inactivation of acid-adapted and nonadapted Escherichia coli O157:H7 during drying and storage of beef jerky treated with different marinades. | 2002 Sep |
|
| [Content of free amino acids in blood plasma of the clean-up personnel at the Chernobyl nuclear power plant accident]. | 2002 Sep-Oct |
|
| Total calcium content of sacs associated with inguinal hernia, hydrocele or undescended testis reflects differences dictated by programmed cell death. | 2003 |
|
| Peritoneal dialysis solutions inhibit the differentiation and maturation of human monocyte-derived dendritic cells: effect of lactate and glucose-degradation products. | 2003 Apr |
|
| Inhibition of nonproteolytic, psychrotrophic clostridia and anaerobic sporeformers by sodium diacetate and sodium lactate in cook-in-bag turkey breast. | 2003 Aug |
|
| Use of organic acids for the control of Clostridium perfringens in cooked vacuum-packaged restructured roast beef during an alternative cooling procedure. | 2003 Aug |
|
| Flicker light-induced vasodilatation in the human retina: effect of lactate and changes in mean arterial pressure. | 2003 Dec |
|
| Lactate depresses sarcolemmal permeability of Ca2+ in intact arterial smooth muscle. | 2003 Dec 19 |
|
| Selective enumeration of Lactobacillus delbrueckii ssp. bulgaricus, Streptococcus thermophilus, Lactobacillus acidophilus, bifidobacteria, Lactobacillus casei, Lactobacillus rhamnosus, and propionibacteria. | 2003 Jul |
|
| Correlates of therapeutic response in panic disorder presenting with palpitations: heart rate variability, sleep, and placebo effect. | 2003 Jul |
|
| pH and energy dependent transport of ketoprofen across rat jejunum in vitro. | 2003 Jul |
|
| Lactate: a preferred fuel for human brain metabolism in vivo. | 2003 Jun |
|
| Acid diffusion through extracellular polysaccharides produced by various mutants of Streptococcus mutans. | 2003 Jun |
|
| [Na+ overload-induced mitochondrial dysfunction in myocardial ischemia/reperfusion injury]. | 2003 May |
|
| Growth and germination of proteolytic Clostridium botulinum in vegetable-based media. | 2003 May |
|
| Predictive model for the combined effect of temperature, sodium lactate, and sodium diacetate on the heat resistance of Listeria monocytogenes in beef. | 2003 May |
|
| Coping strategies of panic and control subjects undergoing lactate infusion during magnetic resonance imaging confinement. | 2003 May-Jun |
|
| Radiation (gamma) resistance and postirradiation growth of Listeria monocytogenes suspended in beef bologna containing sodium diacetate and potassium lactate. | 2003 Nov |
|
| Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization. | 2003 Nov |
|
| [Application of sorbilact for treatment of postoperative paralytic ileus in cancer of the esophagus and stomach]. | 2003 Sep |
|
| [Experimental provocation of panic attacks as a human experimental model for anxiety]. | 2003 Sep |
|
| Effect of intravenous administration of sodium-lactate on retinal blood flow in healthy subjects. | 2003 Sep |
|
| Influence of marinades on survival during storage of acid-adapted and nonadapted Listeria monocytogenes inoculated post-drying on beef jerky. | 2003 Sep 15 |
|
| Thermal resistances and lactate and diacetate sensitivities of bacteria causing bologna discolouration. | 2003 Sep 15 |
|
| Antimicrobial activity of enterocin EJ97 against 'Bacillus macroides/Bacillus maroccanus' isolated from zucchini purée. | 2004 |
|
| Factors that contribute to the botulinal safety of reduced-fat and fat-free process chesse products. | 2004 Aug |
|
| Preservation of mitochondrial function during ischemia as a possible mechanism for cardioprotection of diltiazem against ischemia/reperfusion injury. | 2004 Feb 1 |
|
| Effects of ingestion of bicarbonate, citrate, lactate, and chloride on sprint running. | 2004 Jul |
|
| Electrolyte mass balance during CVVH: lactate vs. bicarbonate-buffered replacement fluids. | 2004 Mar |
|
| An enzymatic route to produce pyruvate from lactate. | 2004 Nov |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:19:57 GMT 2023
by
admin
on
Sat Dec 16 08:19:57 GMT 2023
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| Record UNII |
ALP309P6NE
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| Record Status |
Validated (UNII)
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| Record Version |
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16004
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311-80-8
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DTXSID301264676
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5460179
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1977-18-0
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ALP309P6NE
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