Freneslerbart

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National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:36:11 GMT 2025` Edited by `admin` on `Wed Apr 02 02:36:11 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AL6PH7LX2Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

REGN-1908

Preferred Name

English

Freneslerbart

Official Name

English

freneslerbart [INN]

Common Name

English

Immunoglobulin G4 [227-proline], anti-(Felis catus allergen Fel d1) (human monoclonal REGN1908 ?4-chain), disulfide with human monoclonal REGN1908 ?-chain, dimer

Common Name

English

REGN1908

Code

English

ANTI-CAT ALLERGEN FEL D 1 MONOCLONAL ANITBODY REGN-1908

Common Name

English

Code System Code Type Description

FDA UNII

AL6PH7LX2Y

Created by admin on Wed Apr 02 02:36:12 GMT 2025 , Edited by admin on Wed Apr 02 02:36:12 GMT 2025

PRIMARY

NCI_THESAURUS

C190340

Created by admin on Wed Apr 02 02:36:12 GMT 2025 , Edited by admin on Wed Apr 02 02:36:12 GMT 2025

PRIMARY

INN

12255

Created by admin on Wed Apr 02 02:36:12 GMT 2025 , Edited by admin on Wed Apr 02 02:36:12 GMT 2025

PRIMARY

SMS_ID

300000041921

Created by admin on Wed Apr 02 02:36:12 GMT 2025 , Edited by admin on Wed Apr 02 02:36:12 GMT 2025

PRIMARY

CAS

2453195-94-1

Created by admin on Wed Apr 02 02:36:12 GMT 2025 , Edited by admin on Wed Apr 02 02:36:12 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_133	4_214
2_146	2_202
2_260	2_320
1_133	3_214
2_366	2_424
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_146	1_202
1_225	2_225
1_228	2_228
1_260	1_320
1_366	1_424

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					G408EE88II

ALLERGEN FEL D 1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					AL6PH7LX2Y

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_446] [2_446]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL