AZINTAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H14ClN3OS
Molecular Weight	259.756
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)C(=O)CSC1=NN=C(Cl)C=C1

InChI

InChIKey=SSLKKMZJCJBOML-UHFFFAOYSA-N

InChI=1S/C10H14ClN3OS/c1-3-14(4-2)10(15)7-16-9-6-5-8(11)12-13-9/h5-6H,3-4,7H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C10H14ClN3OS
Molecular Weight	259.756
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6628788 | https://www.ncbi.nlm.nih.gov/pubmed/21600084

Azintamide was initially studied as a therapeutic agent in psoriasis vulgaris. Then was shown, the drug was effective and safe in the treatment of patients with dyspepsia symptoms by the modulation of visceral sensitivity and/or gastrointestinal motility.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
dyspepsia symptoms 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19080231	Primary		Not Provided 511	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
[Efficacy and safety of compound azintamide on dyspepsia symptoms in a multicentre self-controlled trial].	2008-11	19080231
Gas-liquid chromatographic determination of azintamide (Ora-gallin) in pharmaceutical formulations.	1985-05-24	4008559
[Azintamid as a therapeutic agent in psoriasis vulgaris - a therapeutic study].	1983	6628788

Sample Use Guides

In Vivo Use Guide

Two tablets of compound azintamide were administered orally following a meal, tid for 2 weeks

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Wed Apr 02 07:55:32 GMT 2025` Edited by `admin` on `Wed Apr 02 07:55:32 GMT 2025`
Record UNII	ACZ6L64B41
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

COLERIN

Preferred Name

English

AZINTAMIDE

Official Name

English

2-((6-CHLORO-3-PYRIDAZINYL)THIO)-N,N-DIETHYLACETAMIDE

Systematic Name

English

NSC-291837

Code

English

Azintamide [WHO-DD]

Common Name

English

ST 9067

Code

English

AZINTAMIDE [MART.]

Common Name

English

AZINTAMIDE [MI]

Common Name

English

AZINTHIAMIDE

Common Name

English

azintamide [INN]

Common Name

English

ST-9067

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C66913