FENOXEDIL

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H42N2O5
Molecular Weight	486.6435
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCOC1=CC=C(OCC(=O)N(CCN(CC)CC)C2=CC(OCC)=CC=C2OCC)C=C1

InChI

InChIKey=OBQUKWIVMOIRGG-UHFFFAOYSA-N

InChI=1S/C28H42N2O5/c1-6-11-20-34-23-12-14-24(15-13-23)35-22-28(31)30(19-18-29(7-2)8-3)26-21-25(32-9-4)16-17-27(26)33-10-5/h12-17,21H,6-11,18-20,22H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C28H42N2O5
Molecular Weight	486.6435
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4004096 | https://www.ncbi.nlm.nih.gov/pubmed/6412647 | https://www.ncbi.nlm.nih.gov/pubmed/6422897 | https://www.ncbi.nlm.nih.gov/pubmed/64236 |

Fenoxedil is a quinidine-like agent that has a very strong class I antiarrhythmic effect, to the point that it is now almost abandoned after having given toxicity accidents.

Approval Year

PubMed

Title	Date	PubMed
[Treatment of atrial fibrillation with fenoxedil hydrochloride. Apropos of 112 cases].	1984 Jan	6422897

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:01:57 UTC 2023` Edited by `admin` on `Fri Dec 15 16:01:57 UTC 2023`
Record UNII	ABX8234H6M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FENOXEDIL

Official Name

English

fenoxedil [INN]

Common Name

English

FENOXEDIL [MI]

Common Name

English

2-(P-BUTOXYPHENOXY)-N-(2,5-DIETHOXYPHENYL)-N-(2-(DIETHYLAMINO)ETHYL)ACETAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707