LISADIMATE

US Previously Marketed

Details

Stereochemistry	RACEMIC
Molecular Formula	C10H13NO4
Molecular Weight	211.2145
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=CC=C(C=C1)C(=O)OCC(O)CO

InChI

InChIKey=WHQOKFZWSDOTQP-UHFFFAOYSA-N

InChI=1S/C10H13NO4/c11-8-3-1-7(2-4-8)10(14)15-6-9(13)5-12/h1-4,9,12-13H,5-6,11H2

HIDE SMILES / InChI

Molecular Formula	C10H13NO4
Molecular Weight	211.2145
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1087901 | https://www.ncbi.nlm.nih.gov/pubmed/143246

Lisadimate (glyceryl PABA), a substituted aminobenzoate, is a sunscreen with actions similar to those of aminobenzoic acid. It is effective against UVB light. Glyceryl PABA (Escalol 106), present in many popular sunscreens, is a common sensitizer which invariably cross-reacts with benzocaine; it is present in over 400 over-the-counter products. Glyceryl PABA does not appear to cross-react with the sunscreening agents amyl (Escalol 506) and octyl (Escalol 507) dimethyl PABA. Glyceryl PABA, may, on occasion, cross-react with para-aminobenzoic acid (PABA), paraphenylenediamine, aniline, and sulfa drugs. Ironically, the sunscreening agent glyceryl PABA may, itself, act as a photosensitizing agent.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Sunburn 84 Sources: https://www.drugs.com/cons/sunscreen-agent-topical-application.html	Preventing		Approved 8583	Unknown Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
3B Scientific (Wuhan) Corp	3B8-01193	http://www.3bsc.com/index/pro_info.php?id=73128
Alfa Chemistry	136-44-7	https://www.alfa-chemistry.com/cas_136-44-7.htm
Alfa Chemistry	29593-08-6	https://www.alfa-chemistry.com/cas_29593-08-6.htm
Aurora Fine Chemicals LLC	A14.111.429	http://online.aurorafinechemicals.com/info?ID=A14.111.429
Aurora Fine Chemicals LLC	A17.949.810	http://online.aurorafinechemicals.com/info?ID=A17.949.810
BLD Pharm	BD01360496	http://www.bldpharm.com/products/29593-08-6.html
ChemMol	49415905	http://www.chemmol.com/chemmol/49415905.html
Chemspace	CSSB00012337706	https://chem-space.com/CSSB00012337706
Parchem	38142	https://www.parchem.com/chemical-supplier-distributor/Glyceryl-PABA-038142.aspx
Sigma-Aldrich	PH011337_ALDRICH	https://www.sigmaaldrich.com/catalog/product/aldrich/ph011337
Smolecule	S533287	http://www.smolecule.com/products/s533287
THE BioTek	bt-273247	https://www.thebiotek.com/product/inhibitors/bt-273247

PubMed

Title	Date	PubMed
Photocontact allergy to benzocaine.	1981-02	6970547
Contact allergy/photo allergy to glyceryl PABA and benzocaine.	1978-12	153828
The presence of benzocaine in sunscreens containing glyceryl PABA (Escalol 106)	1977-09	143246

Patents

Sample Use Guides

In Vivo Use Guide

Sunscreen products containing lisadimate should be applied 1 to 2 hours before sun exposure.

Route of Administration: Topical

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:05:12 GMT 2025` Edited by `admin` on `Wed Apr 02 09:05:12 GMT 2025`
Record UNII	A886B5N5IM
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GLYCERYL PABA

Preferred Name

English

LISADIMATE

Official Name

English

(±)-GLYCEROL 1-(P-AMINOBENZOATE)

Common Name

English

GLYCERYL P-AMINOBENZOATE [MI]

Common Name

English

LISADIMATE [USAN]

Common Name

English

1,2,3-PROPANETRIOL, 1-(4-AMINOBENZOATE), (±)-

Common Name

English

LISADIMATE [MART.]

Common Name

English

GLYCERYL P-AMINOBENZOATE

Common Name

English

lisadimate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C851