ZK-93423 hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H22N2O4.ClH
Molecular Weight	426.893
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCOC(=O)C1=C(COC)C2=C(NC3=C2C=C(OCC4=CC=CC=C4)C=C3)C=N1

InChI

InChIKey=KHMDBPAODAAMBQ-UHFFFAOYSA-N

InChI=1S/C23H22N2O4.ClH/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22;/h4-12,25H,3,13-14H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C23H22N2O4
Molecular Weight	390.4318
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
GABA-A receptor; alpha-3/beta-3/gamma-2 11 Target ID: CHEMBL2094120 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9651158 \| https://adisinsight.springer.com/drugs/800000551	Agonist 2678	6.0 nM [Ki]
GABA-A receptor; alpha-1/beta-3/gamma-2 16 Target ID: CHEMBL2094121 Sources: https://adisinsight.springer.com/drugs/800000551 \| https://www.ncbi.nlm.nih.gov/pubmed/9651158	Agonist 2678	4.1 nM [Ki]
GABA-A receptor; alpha-2/beta-3/gamma-2 12 Target ID: CHEMBL2094130 Sources: https://adisinsight.springer.com/drugs/800000551 \| https://www.ncbi.nlm.nih.gov/pubmed/9651158	Agonist 2678	4.2 nM [Ki]
GABA-A receptor; alpha-5/beta-3/gamma-2 14 Target ID: CHEMBL2094122 Sources: https://adisinsight.springer.com/drugs/800000551 \| https://www.ncbi.nlm.nih.gov/pubmed/9651158	Agonist 2678	4.5 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:17:10 GMT 2023` Edited by `admin` on `Sat Dec 16 19:17:10 GMT 2023`
Record UNII	A84JFN7GNH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZK-93423 hydrochloride

Code

English

9H-Pyrido[3,4-b]indole-3-carboxylic acid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl ester, hydrochloride (1:1)

Systematic Name

English

ZK93423 hydrochloride

Code

English

4-(Methoxymethyl)-6-(phenylmethoxy)-9H-pyrido[3,4-b]indole-3-carboxylicacidethylesterhydrochloride

Systematic Name

English

ethyl 6-(benzyloxy)-4-(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylate hydrochloride

Systematic Name

English

Code System Code Type Description

PUBCHEM

56972166

Created by admin on Sat Dec 16 19:17:10 GMT 2023 , Edited by admin on Sat Dec 16 19:17:10 GMT 2023

PRIMARY

FDA UNII

A84JFN7GNH

Created by admin on Sat Dec 16 19:17:10 GMT 2023 , Edited by admin on Sat Dec 16 19:17:10 GMT 2023

PRIMARY

CAS

1216574-52-5

Created by admin on Sat Dec 16 19:17:10 GMT 2023 , Edited by admin on Sat Dec 16 19:17:10 GMT 2023

PRIMARY

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ZK-93423

PARENT -> SALT/SOLVATE

Amount: