ZK-93423

CCOC(=O)C1=C(COC)C2=C(NC3=C2C=C(OCC4=CC=CC=C4)C=C3)C=N1

InChIKey=ALBKMJDFBZVHAK-UHFFFAOYSA-N

InChI=1S/C23H22N2O4/c1-3-28-23(26)22-18(14-27-2)21-17-11-16(29-13-15-7-5-4-6-8-15)9-10-19(17)25-20(21)12-24-22/h4-12,25H,3,13-14H2,1-2H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
GABA-A receptor; alpha-3/beta-3/gamma-2 11 Target ID: CHEMBL2094120 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9651158 \| https://adisinsight.springer.com/drugs/800000551	Agonist 2678	6.0 nM [Ki]
GABA-A receptor; alpha-1/beta-3/gamma-2 16 Target ID: CHEMBL2094121 Sources: https://adisinsight.springer.com/drugs/800000551 \| https://www.ncbi.nlm.nih.gov/pubmed/9651158	Agonist 2678	4.1 nM [Ki]
GABA-A receptor; alpha-2/beta-3/gamma-2 12 Target ID: CHEMBL2094130 Sources: https://adisinsight.springer.com/drugs/800000551 \| https://www.ncbi.nlm.nih.gov/pubmed/9651158	Agonist 2678	4.2 nM [Ki]
GABA-A receptor; alpha-5/beta-3/gamma-2 14 Target ID: CHEMBL2094122 Sources: https://adisinsight.springer.com/drugs/800000551 \| https://www.ncbi.nlm.nih.gov/pubmed/9651158	Agonist 2678	4.5 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:27:43 GMT 2023` Edited by `admin` on `Sat Dec 16 19:27:43 GMT 2023`
Record UNII	B6PWX5B47Q
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ZK-93423

Code

English

ZK93423

Code

English

9H-Pyrido[3,4-b]indole-3-carboxylic acid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl ester

Systematic Name

English

Ethyl 4-(methoxymethyl)-6-(phenylmethoxy)-9H-pyrido[3,4-b]indole-3-carboxylate

Systematic Name

English

Ethyl 6-Benzyloxy-4-methoxymethyl-β-carboline-3-carboxylate

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID101004052