ELISARTAN POTASSIUM

Details

Stereochemistry	RACEMIC
Molecular Formula	C27H28ClN6O5.K
Molecular Weight	591.1
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[K+].CCCCC1=NC(Cl)=C(N1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[N-]4)C(=O)OC(C)OC(=O)OCC

InChI

InChIKey=LWBGIHXLGBYBNG-UHFFFAOYSA-N

InChI=1S/C27H28ClN6O5.K/c1-4-6-11-22-29-24(28)23(26(35)38-17(3)39-27(36)37-5-2)34(22)16-18-12-14-19(15-13-18)20-9-7-8-10-21(20)25-30-32-33-31-25;/h7-10,12-15,17H,4-6,11,16H2,1-3H3;/q-1;+1

HIDE SMILES / InChI

Molecular Formula	C27H29ClN6O5
Molecular Weight	553.009
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	K
Molecular Weight	39.0983
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800002994 | https://www.ncbi.nlm.nih.gov/pubmed/8703667

Elisartan (HN 65021) is a selective, orally active, nonpeptide angiotensin II (AT1) antagonist. It antagonizes angiotensin receptor-mediated vasoconstriction. Elisartan was being assessed for the treatment of hypertension.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Type-1 angiotensin II receptor 40 Target ID: P30556 Gene ID: 185.0 Gene Symbol: AGTR1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/8703667	Antagonist 2778

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:53:19 GMT 2023` Edited by `admin` on `Fri Dec 15 15:53:19 GMT 2023`
Record UNII	A6ZX50P1U1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ELISARTAN POTASSIUM

Common Name

English

1H-IMIDAZOLE-5-CARBOXYLIC ACID, 2-BUTYL-4-CHLORO-1-((2'-(1H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-, 1-((ETHOXYCARBONYL)OXY)ETHYL ESTER, POTASSIUM SALT, (±)-

Systematic Name

English

ELISARTAN POTASSIUM, (±)-

Common Name

English

1-(ETHOXYCARBONYLOXY)ETHYL 2-BUTYL-4-CHLORO-((2'-(1H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-1H-IMIDAZOLE-5-CARBOXYLATE POTASSIUM

Systematic Name

English

Code System Code Type Description

CAS

154568-18-0

Created by admin on Fri Dec 15 15:53:20 GMT 2023 , Edited by admin on Fri Dec 15 15:53:20 GMT 2023

PRIMARY

FDA UNII

A6ZX50P1U1

Created by admin on Fri Dec 15 15:53:20 GMT 2023 , Edited by admin on Fri Dec 15 15:53:20 GMT 2023

PRIMARY

PUBCHEM

23663417

Created by admin on Fri Dec 15 15:53:20 GMT 2023 , Edited by admin on Fri Dec 15 15:53:20 GMT 2023

PRIMARY

Related Record Type Details


					WCC8Z95027

ELISARTAN

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Amount:

Related Record Type Details


					WCC8Z95027

ELISARTAN

ACTIVE MOIETY

Amount:

Details

SMILES

InChI

DescriptionSources: https://adisinsight.springer.com/drugs/800002994 | https://www.ncbi.nlm.nih.gov/pubmed/8703667

Originator

Approval Year

Targets

PubMed

Description
Sources: https://adisinsight.springer.com/drugs/800002994 | https://www.ncbi.nlm.nih.gov/pubmed/8703667