METHOPROMAZINE

COC1=CC2=C(SC3=C(C=CC=C3)N2CCCN(C)C)C=C1

InChIKey=BRABPYPSZVCCLR-UHFFFAOYSA-N

InChI=1S/C18H22N2OS/c1-19(2)11-6-12-20-15-7-4-5-8-17(15)22-18-10-9-14(21-3)13-16(18)20/h4-5,7-10,13H,6,11-12H2,1-3H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Methopromazine was developed as a neuroleptic agent with antipsychotic activity. Information about the current use of this compound is not available.

Doses

Dose	Population	Adverse events
1200 mg 1 times / day multiple, oral Studied dose Dose: 1200 mg, 1 times / day Route: oral Route: multiple Dose: 1200 mg, 1 times / day Sources: https://pubmed.ncbi.nlm.nih.gov/13637265	unhealthy, 20-50 years Health Status: unhealthy Age Group: 20-50 years Sex: F Sources: https://pubmed.ncbi.nlm.nih.gov/13637265	Sources: https://pubmed.ncbi.nlm.nih.gov/13637265

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1O5G37
Chemieliva Pharmaceutical Co., Ltd	PBCM1280010
LGC Standards	LGCFOR1887.00	https://www.lgcstandards.com/US/en/p/LGCFOR1887.00
NovoSeek	6433365
PubChem	6433365	https://pubchem.ncbi.nlm.nih.gov/compound/6433365

PubMed

Title	Date	PubMed
Application of methopromazine for the extractive spectrophotometric determination of platinum.	1983-07	18963412
[Methopromazine and adrenalin vasodilatation].	1961	13888143
[Pharmacological study of a new derivative of phenothiazine, 4632 RP or methopromazine].	1957	13585712
[Pharmacodynamic properties of methopromazine, new neuroleptic related to chlorpromazine].	1957	13489953

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:17:54 GMT 2025` Edited by `admin` on `Mon Mar 31 19:17:54 GMT 2025`
Record UNII	A6F645Q9HQ
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

METHOPROMAZINE

Official Name

English

METHOXYPROMAZINE

Preferred Name

English

10-(3-DIMETHYLAMINOPROPYL)-2-METHOXYPHENOTHIAZINE

Systematic Name

English

METHOXYPROMAZINE [MI]

Common Name

English

methopromazine [INN]

Common Name

English

Methopromazine [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

18847