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Details

Stereochemistry RACEMIC
Molecular Formula C15H20N2O4S
Molecular Weight 324.395
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SUMACETAMOL

SMILES

CSCCC(NC(C)=O)C(=O)OC1=CC=C(NC(C)=O)C=C1

InChI

InChIKey=GDRGOYFISYGSHQ-UHFFFAOYSA-N
InChI=1S/C15H20N2O4S/c1-10(18)16-12-4-6-13(7-5-12)21-15(20)14(8-9-22-3)17-11(2)19/h4-7,14H,8-9H2,1-3H3,(H,16,18)(H,17,19)

HIDE SMILES / InChI

Molecular Formula C15H20N2O4S
Molecular Weight 324.395
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Sumacetamol is a acetylaminothioalkanoate derivative patented by Sterwin A.-G. as an analgesic and antipyretic agent. Sumacetamol is used in combination with free paracetamol. In clinical trials, Sumacetamol failed to demonstrate superior efficacy in pain and swelling management compare to paracetamol but shows a longer duration of analgesia. The rates of reported adverse events were similar in paracetamol and Sumacetamol, although reports of mild to moderate drowsiness were more common after the Sumacetamol combination.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
b.i.d. (equivalent to 2 g paracetamol X 2)
Route of Administration: Oral
Substance Class Chemical
Record UNII
A0BK6FM64M
Record Status Validated (UNII)
Record Version