Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C25H26N6O4S.CH4O3S |
| Molecular Weight | 602.682 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(O)(=O)=O.COC1=CC2=NC(=NC(N)=C2C(C3=CC=CC=N3)=C1OC)N4CCC5=C(C4)C=CC=C5NS(C)(=O)=O
InChI
InChIKey=PELLFYXDXSYSSE-UHFFFAOYSA-N
InChI=1S/C25H26N6O4S.CH4O3S/c1-34-20-13-19-22(21(23(20)35-2)18-8-4-5-11-27-18)24(26)29-25(28-19)31-12-10-16-15(14-31)7-6-9-17(16)30-36(3,32)33;1-5(2,3)4/h4-9,11,13,30H,10,12,14H2,1-3H3,(H2,26,28,29);1H3,(H,2,3,4)
| Molecular Formula | CH4O3S |
| Molecular Weight | 96.106 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C25H26N6O4S |
| Molecular Weight | 506.577 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Investigation of regional mechanisms responsible for poor oral absorption in humans of a modified release preparation of the alpha-adrenoreceptor antagonist, 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003): the rational use of ex vivo intestine to predict in vivo absorption. | 2008-01 |
|
| Impact of physicochemical and structural properties on the pharmacokinetics of a series of alpha1L-adrenoceptor antagonists. | 2007-08 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:12:35 GMT 2025
by
admin
on
Mon Mar 31 18:12:35 GMT 2025
|
| Record UNII |
9YMP2G22X1
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
9YMP2G22X1
Created by
admin on Mon Mar 31 18:12:35 GMT 2025 , Edited by admin on Mon Mar 31 18:12:35 GMT 2025
|
PRIMARY | |||
|
358632-25-4
Created by
admin on Mon Mar 31 18:12:35 GMT 2025 , Edited by admin on Mon Mar 31 18:12:35 GMT 2025
|
PRIMARY | |||
|
9830194
Created by
admin on Mon Mar 31 18:12:35 GMT 2025 , Edited by admin on Mon Mar 31 18:12:35 GMT 2025
|
PRIMARY | |||
|
DTXSID60431391
Created by
admin on Mon Mar 31 18:12:35 GMT 2025 , Edited by admin on Mon Mar 31 18:12:35 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |