Details
Stereochemistry | ACHIRAL |
Molecular Formula | C18H14I2O4 |
Molecular Weight | 548.1103 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C(CC2=CC(I)=C(OCC(O)=O)C(I)=C2)C3=CC=CC=C3O1
InChI
InChIKey=OLIKCJUMYWSDIV-UHFFFAOYSA-N
InChI=1S/C18H14I2O4/c1-10-13(12-4-2-3-5-16(12)24-10)6-11-7-14(19)18(15(20)8-11)23-9-17(21)22/h2-5,7-8H,6,9H2,1H3,(H,21,22)
Molecular Formula | C18H14I2O4 |
Molecular Weight | 548.1103 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Synthesis and preliminary characterization of a novel antiarrhythmic compound (KB130015) with an improved toxicity profile compared with amiodarone. | 2002 Jan 31 |
|
Inhibition of G protein-coupled and ATP-sensitive potassium currents by 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015), an amiodarone derivative. | 2004 Jan |
|
The amiodarone derivative 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015) opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle. | 2007 Jan 26 |
|
The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism. | 2010 Apr 25 |
|
Identifying regulators for EAG1 channels with a novel electrophysiology and tryptophan fluorescence based screen. | 2010 Sep 2 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:01:57 GMT 2023
by
admin
on
Sat Dec 16 08:01:57 GMT 2023
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Record UNII |
9YA9HD8JR2
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Record Status |
Validated (UNII)
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Record Version |
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9YA9HD8JR2
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147030-48-6
Created by
admin on Sat Dec 16 08:01:57 GMT 2023 , Edited by admin on Sat Dec 16 08:01:57 GMT 2023
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