U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C21H25N3O3
Molecular Weight 367.4415
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIRACIZINE

SMILES

CCOC(=O)NC1=CC2=C(CCC3=CC=CC=C3N2C(=O)CN(C)C)C=C1

InChI

InChIKey=KJAMZCVTJDTESW-UHFFFAOYSA-N
InChI=1S/C21H25N3O3/c1-4-27-21(26)22-17-12-11-16-10-9-15-7-5-6-8-18(15)24(19(16)13-17)20(25)14-23(2)3/h5-8,11-13H,4,9-10,14H2,1-3H3,(H,22,26)

HIDE SMILES / InChI

Molecular Formula C21H25N3O3
Molecular Weight 367.4415
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tiracizine a drug belongs to the new class I antiarrhythmic agent was studied in patients with ischemic heart disease, where was shown, that the drug could decrease myocardial contractile function.

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
7-day multiple-dose study period (50 mg tiracizine twice daily)
Route of Administration: Oral
Substance Class Chemical
Record UNII
9UUO2T61K7
Record Status Validated (UNII)
Record Version