NICOTINYL ALCOHOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H7NO
Molecular Weight	109.1259
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

OCC1=CN=CC=C1

InChI

InChIKey=MVQVNTPHUGQQHK-UHFFFAOYSA-N

InChI=1S/C6H7NO/c8-5-6-2-1-3-7-4-6/h1-4,8H,5H2

HIDE SMILES / InChI

Molecular Formula	C6H7NO
Molecular Weight	109.1259
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Nicotinyl alcohol is a direct-acting vasolidator, that may decrease the blood pressure and it is a cholesterol-lowering agent. Nicotinyl alcohol as a tartrate salt led to the efficiency improvements in patients with intermittent claudication. In addition, nicotinyl alcohol alone or associated with other drugs was studied in the treatment of radicular syndromes; and was shown, that the effect had not been due to mechanical compression.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Intermittent claudication 12	Primary		Not Provided 504	ronicol
Radicular syndromes 5	Primary		Not Provided 504	Unknown

Doses

Show entries

Dose	Population	Adverse events
600 mg 2 times / day steady, oral Recommended	unhealthy, 30 - 66 years	Other AEs: Increased appetite, Skin rash...

Showing 1 to 1 of 1 entries

Previous1Next

AEs

Show entries

AE	Significance	Dose	Population
Abdominal pain	15%	600 mg 2 times / day steady, oral Recommended	unhealthy, 30 - 66 years
Increased appetite	15%	600 mg 2 times / day steady, oral Recommended	unhealthy, 30 - 66 years
Skin rash	36%	600 mg 2 times / day steady, oral Recommended	unhealthy, 30 - 66 years
Itching	37%	600 mg 2 times / day steady, oral Recommended	unhealthy, 30 - 66 years
Nausea	50%	600 mg 2 times / day steady, oral Recommended	unhealthy, 30 - 66 years

Showing 1 to 5 of 6 entries

Previous1 2Next

Sourcing

Sourcing

Show entries

Vendor/Aggregator	ID	URL
001 Chemical	NO22409	https://www.001chemical.com/chem/100-55-0
3B Scientific (Wuhan) Corp	3B3-010708	http://www.3bsc.com/index/pro_info.php?id=33201
AA Blocks	AA00004J	http://www.aablocks.com/goods/Goods/detail?id=AA00004J
Aaron Chemicals	AR0000WB	http://www.aaronchem.com/100-55-0
abcr GmbH	AB121175	http://www.abcr.de/shop/en/AB121175

Showing 1 to 5 of 76 entries

Previous1 2 3 4 5…16Next

PubMed

Show entries

Title	Date	PubMed
Importance of free fatty acids as a determinant of myocardial oxygen consumption and myocardial ischemic injury during norepinephrine infusion in dogs.	1974 May	4825226
The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.	2010 Jan	19853978