FR-144633

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H28N4O7
Molecular Weight	436.4589
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CCCOC1=CC=C(C=C1)C(N)=N)C(O)=O

InChI

InChIKey=JFCXCBBSUORTNS-YOEHRIQHSA-N

InChI=1S/C20H28N4O7/c1-11(2)17(20(29)30)24-19(28)14(10-16(26)27)23-15(25)4-3-9-31-13-7-5-12(6-8-13)18(21)22/h5-8,11,14,17H,3-4,9-10H2,1-2H3,(H3,21,22)(H,23,25)(H,24,28)(H,26,27)(H,29,30)/t14-,17-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H28N4O7
Molecular Weight	436.4589
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Platelet anaesthesia during extracorporeal circulation: differential effects of GP IIb/IIIa blockers on platelet activation marker P-selectin expression at hypothermia.	2008	18304613
Invited commentary.	2005-07	15975377
Platelet preservation with a glycoprotein IIb/IIIa inhibitor in a porcine cardiopulmonary bypass model.	2005-07	15975376
Efficacy of FK633, an ultra-short acting glycoprotein IIb/IIIa antagonist on platelet preservation during and after cardiopulmonary bypass.	2004-08	15296885
The state of platelets preserved in extracorporeal circulation with a glycoprotein IIb/IIIa inhibitor.	2004	15183042
Pharmacologic platelet anesthesia by glycoprotein IIb/IIIa complex antagonist and argatroban during in vitro extracorporeal circulation.	2003-08	12928640
A naturally occurring Tyr143His alpha IIb mutation abolishes alpha IIb beta 3 function for soluble ligands but retains its ability for mediating cell adhesion and clot retraction: comparison with other mutations causing ligand-binding defects.	2003-05-01	12506038

Substance Class	Chemical Created by `admin` on `Wed Apr 02 11:18:35 GMT 2025` Edited by `admin` on `Wed Apr 02 11:18:35 GMT 2025`
Record UNII	9SP2H336UF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FK-633

Preferred Name

English

FR-144633

Code

English

FR144633

Code

English

N-(4-(4-(AMINOIMINOMETHYL)PHENOXY)-1-OXOBUTYL)-L-.ALPHA.-ASPARTYL-L-VALINE

Systematic Name

English

FK633

Code

English

L-VALINE, N-(N-(4-(4-(AMINOIMINOMETHYL)PHENOXY)-1-OXOBUTYL)-L-.ALPHA.-ASPARTYL)-

Systematic Name

English

(2S)-2-((2S)-2-(4-(4-CARBAMIMIDOYLPHENOXY)BUTANAMIDO)-3-CARBOXYPROPANAMIDO)-3-METHYLBUTANOIC ACID

Systematic Name

English

Code System Code Type Description

MANUFACTURER PRODUCT INFORMATION

FK-633