ELAPEGADEMASE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:48:09 GMT 2025` Edited by `admin` on `Tue Apr 01 18:48:09 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	9R3D3Y0UHS
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

elapegademase [INN]

Preferred Name

English

ELAPEGADEMASE

Official Name

English

ELAPEGADEMASE [USAN]

Common Name

English

Elapegademase [WHO-DD]

Common Name

English

POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-CARBOXY-.OMEGA.-METHOXY-, AMIDE WITH ADENOSINE DEAMINASE (SYNTHETIC)

Systematic Name

English

(CYS74>SER,ALA245>THR)ADENOSINE DEAMINASE (BOS TAURUS, BOVINE)-(1-356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN AVERAGE OFAPPROXIMATELY 13 .OMEGA.-METHOXYPOLY(O

Systematic Name

English

EZN2279

Code

English

(74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH

Systematic Name

English

ELAPEGADEMASE [JAN]

Common Name

English

EZN-2279

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

570316

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

FDA ORPHAN DRUG

467514

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

Code System Code Type Description

DRUG CENTRAL

5318

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

INN

10378

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

RXCUI

2059218

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

ALTERNATIVE

RXCUI

2059219

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

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USAN

EF-12

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

DAILYMED

9R3D3Y0UHS

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

CAS

1709806-75-6

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

DRUG BANK

DB14712

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

LACTMED

Elapegademase

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

PUBCHEM

121488177

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

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WIKIPEDIA

Elapegademase

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

FDA UNII

9R3D3Y0UHS

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

SMS_ID

100000174552

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

NCI_THESAURUS

C171787

Created by admin on Tue Apr 01 18:48:09 GMT 2025 , Edited by admin on Tue Apr 01 18:48:09 GMT 2025

PRIMARY

Related Record Type Details

ELAPEGADEMASE-LVLR

SUB_CONCEPT->SUBSTANCE

Amount:

ELAPEGADEMASE-LVLR

INNOVATOR->PARENT

Amount:

Related Record Type Details


					9R3D3Y0UHS

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION			K	Amount:	MPEG 5000 LYSINE	1V678321PC
AMINO ACID SUBSTITUTION	[1_1]		A	Amount:	N-(MPEG-5000)-ALANINE	KYP267E0LL

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL