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Details

Stereochemistry ABSOLUTE
Molecular Formula C8H10FN3O3S
Molecular Weight 247.247
Optical Activity ( + )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EMTRICITABINE, (+)-

SMILES

NC1=NC(=O)N(C=C1F)[C@H]2CS[C@@H](CO)O2

InChI

InChIKey=XQSPYNMVSIKCOC-RITPCOANSA-N
InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m1/s1

HIDE SMILES / InChI
Molecular Formula C8H10FN3O3S
Molecular Weight 247.247
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Emtricitabine (minus enantiomer) is a synthetic nucleoside analog of cytosine with activity against HIV-1. It’s more active and significantly less toxic than the (+) enantiomer.

Approval Year

Unknown
139,594

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
9PDN1V466A
Record Status Validated (UNII)
Record Version
NIH
NCATS
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