Details
| Stereochemistry | EPIMERIC |
| Molecular Formula | C21H31NO2 |
| Molecular Weight | 329.4763 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(CC)CCCOC(=O)C1(C[C@@H]2CC[C@H]1C2)C3=CC=CC=C3
InChI
InChIKey=BDNMABJZSXTKAQ-VCPDFFEISA-N
InChI=1S/C21H31NO2/c1-3-22(4-2)13-8-14-24-20(23)21(18-9-6-5-7-10-18)16-17-11-12-19(21)15-17/h5-7,9-10,17,19H,3-4,8,11-16H2,1-2H3/t17-,19+,21?/m1/s1
| Molecular Formula | C21H31NO2 |
| Molecular Weight | 329.4763 |
| Charge | 0 |
| Count |
|
| Stereochemistry | EPIMERIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Bornaptine is a synthetic anticholinergic drug. The compound is a nonselective M1 and M4 antagonist and was shown to inhibit the negative inotropic response to carbachol in the isolated left atrium of the rat with pA2 of 7.27. Bornaprine is used for the treatment of symptoms of Parkinson's disease. A clinical trial showed the superiority of Bornaprine over placebo in reducing parkinsonian tremor. Bornaptine demonstrated positive results in localized hyperhidrosis.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:34:21 GMT 2023
by
admin
on
Fri Dec 15 16:34:21 GMT 2023
|
| Record UNII |
9M363FGA7J
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
WHO-ATC |
N04AA11
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
||
|
NCI_THESAURUS |
C29704
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
||
|
WHO-VATC |
QN04AA11
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
19610
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | RxNorm | ||
|
BORNAPRINE
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
70687267
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
9M363FGA7J
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
SUB05874MIG
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
DB13619
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
C90742
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
20448-86-6
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
CHEMBL2104596
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
100000088655
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
3897
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
C006088
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
390
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY | |||
|
DTXSID801043211
Created by
admin on Fri Dec 15 16:34:21 GMT 2023 , Edited by admin on Fri Dec 15 16:34:21 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
