Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C16H25NO3 |
| Molecular Weight | 279.3746 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(=CC=C1)[C@]2(O)C[C@@H](O)CC[C@H]2CN(C)C
InChI
InChIKey=LQJLLAOISDVBJM-OFQRWUPVSA-N
InChI=1S/C16H25NO3/c1-17(2)11-13-7-8-14(18)10-16(13,19)12-5-4-6-15(9-12)20-3/h4-6,9,13-14,18-19H,7-8,10-11H2,1-3H3/t13-,14-,16+/m0/s1
| Molecular Formula | C16H25NO3 |
| Molecular Weight | 279.3746 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Axomadol is a centrally active analgesic agent with opioid agonistic properties and with inhibitory effects on the reuptake of the monoamines noradrenaline and, to serotonin [5‐hydroxytrypyamine (5‐HT)]. The drug participated in phase II clinical trials in the treatment of patients with moderate to severe chronic low back pain. As a result, the axomadol didn’t meet predetermined study endpoint, and studies were discontinued.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 09:46:28 GMT 2025
by
admin
on
Wed Apr 02 09:46:28 GMT 2025
|
| Record UNII |
9J92U4CVS0
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Preferred Name | English | ||
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Code | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C241
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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300000034163
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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187219-99-4
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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9J92U4CVS0
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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8273
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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15344754
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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DTXSID10171992
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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RR-85
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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CHEMBL2107731
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY | |||
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C72138
Created by
admin on Wed Apr 02 09:46:28 GMT 2025 , Edited by admin on Wed Apr 02 09:46:28 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
