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Details

Stereochemistry ACHIRAL
Molecular Formula Sb
Molecular Weight 121.76
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTIMONY

SMILES

[Sb]

InChI

InChIKey=OUULRIDHGPHMNQ-UHFFFAOYSA-N
InChI=1S/Sb.3H

HIDE SMILES / InChI

Molecular Formula Sb
Molecular Weight 121.76
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Antimony (Sb) is a toxic metalloid that occurs widely at trace concentrations in soil, aquatic systems, and the atmosphere. Antimony is not an abundant element but is found in small quantities in over 100 mineral species. It is most often found as antimony(III) sulfide. Antimony is used in the electronics industry to make some semiconductor devices, such as infrared detectors and diodes. It is alloyed with lead or other metals to improve their hardness and strength. A lead-antimony alloy is used in batteries. Other uses of antimony alloys include type metal (in printing presses), bullets and cable sheathing. Antimony has been in medical use against microbes and parasites as well. Antimony-based drugs have been prescribed against leishmaniasis since the parasitic transmission of the tropical disease was understood in the beginning of the 20th century. As a therapeutic, antimony has been mostly used for the treatment of leishmaniasis and schistosomiasis. The major toxic side-effects of antimonials as a result of therapy are cardiotoxicity (~9% of patients) and pancreatitis, which is seen commonly in HIV and visceral leishmaniasis co-infections.

Approval Year

PubMed

PubMed

TitleDatePubMed
Interleukin 6 during active visceral leishmaniasis and after treatment.
1995 Oct
[American cutaneous leishmaniasis in the Federal District].
1999 Sep-Oct
Mucosal leishmaniasis: quantitative nasal cytology as a marker of disease activity and indicator of healing.
2000 Jan
Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishmaniasis: intracellular adhesion molecule 1-dependent and -independent regulation.
2000 Nov
Interleukin-12 regulates the response to chemotherapy in experimental visceral Leishmaniasis.
2000 Nov
Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels.
2003 May 15
Leishmania major LmACR2 is a pentavalent antimony reductase that confers sensitivity to the drug pentostam.
2004 Sep 3
Classification of heavy-metal toxicity by human DNA microarray analysis.
2007 May 15
Cutaneous leishmaniasis with boggy induration and simultaneous mucosal disease.
2009 Jan
[An adult case of visceral leishmaniasis in a province of Black-Sea region, Turkey].
2010 Oct
Monitoring of intracellular nitric oxide in leishmaniasis: its applicability in patients with visceral leishmaniasis.
2011 Jan
Solubility shift and SUMOylaltion of promyelocytic leukemia (PML) protein in response to arsenic(III) and fate of the SUMOylated PML.
2015 Sep 15
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:17:42 UTC 2023
Edited
by admin
on Fri Dec 15 17:17:42 UTC 2023
Record UNII
9IT35J3UV3
Record Status Validated (UNII)
Record Version
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Name Type Language
ANTIMONY
MI   WHO-DD  
Systematic Name English
Antimony [WHO-DD]
Common Name English
STIBIUM METALLICUM [HPUS]
Common Name English
STIBIUM METALLICUM
HPUS  
Common Name English
SB
Code English
ANTIMONY, ELEMENTAL
HSDB  
Common Name English
STIBIUM
Systematic Name English
C.I. 77050
Code English
PREPARED METALLIC ANTIMONY
Common Name English
ANTIMONY ELEMENT
Common Name English
ANTIMONY BLACK
Common Name English
ANTIMONY, ELEMENTAL [HSDB]
Common Name English
ANTIMONY [MI]
Common Name English
METALLIC ANTIMONY
Common Name English
Classification Tree Code System Code
DSLD 3349 (Number of products:23)
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
CFR 21 CFR 862.3110
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
NCI_THESAURUS C1940
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID5023879
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
CHEBI
30304
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
CHEBI
30513
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
MERCK INDEX
m1953
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY Merck Index
DRUG BANK
DB13110
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
MESH
D000965
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
RXCUI
1311407
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY RxNorm
PUBCHEM
5354495
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
HSDB
508
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
SMS_ID
100000077405
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
DAILYMED
9IT35J3UV3
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
FDA UNII
9IT35J3UV3
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
NCI_THESAURUS
C95187
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-146-5
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
EVMPD
SUB12914MIG
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
CAS
7440-36-0
Created by admin on Fri Dec 15 17:17:42 UTC 2023 , Edited by admin on Fri Dec 15 17:17:42 UTC 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY