PNU-120596

COC1=CC(OC)=C(Cl)C=C1NC(=O)NC2=NOC(C)=C2

InChIKey=CEIIEALEIHQDBX-UHFFFAOYSA-N

InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6H,1-3H3,(H2,15,16,17,18)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Neuronal acetylcholine receptor protein alpha-7 subunit 77 Target ID: CHEMBL2492 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15858066	Positive Allosteric Modulator 179		6.8 null [pEC50]

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:29:33 GMT 2023` Edited by `admin` on `Fri Dec 15 16:29:33 GMT 2023`
Record UNII	9EZT3PTH2J
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

PNU-120596

Common Name

English

NSC-216666

Code

English

UREA, N-(5-CHLORO-2,4-DIMETHOXYPHENYL)-N'-(5-METHYL-3-ISOXAZOLYL)-

Systematic Name

English

1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-METHYLISOXAZOL-3-YL)UREA

Systematic Name

English

N-(5-CHLORO-2,4-DIMETHOXYPHENYL)-N'-(5-METHYL-3-ISOXAZOLYL)-UREA

Systematic Name

English

Code System Code Type Description

CAS

501925-31-1