FENHARMANE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	UNKNOWN
Molecular Formula	C18H18N2
Molecular Weight	262.3489
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENHARMANE

Structure Search

SMILES

C(C1NCCC2=C1NC3=C2C=CC=C3)C4=CC=CC=C4

InChI

InChIKey=LHVNPTMRAQQPID-UHFFFAOYSA-N

InChI=1S/C18H18N2/c1-2-6-13(7-3-1)12-17-18-15(10-11-19-17)14-8-4-5-9-16(14)20-18/h1-9,17,19-20H,10-12H2

HIDE SMILES / InChI

Molecular Formula	C18H18N2
Molecular Weight	262.3489
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5612958 | https://www.ncbi.nlm.nih.gov/pubmed/14477998 | https://www.europsy-journal.com/article/S0924-9338(00)94202-0/pdf

FENHARMANE, a reserpine-like substance, is a neuroleptic developed and clinically tested in the Czech Republic.

CNS Activity

Approval Year

PubMed

PubMed

Title	Date	PubMed
The action of chlorpromazine and amitriptyline on the effects of phenoharmane.	1967-11	5612958
[Nialamid and its combinations with reserpine-like substances (fenoharman, reserpine) in the therapy of endogenous depressions].	1962-07-05	14477998

Sample Use Guides

In Vivo Use Guide

Oral LD50 1200 mg/kg. Intravenous LD50 37 mg/kg.

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:59:51 GMT 2025` Edited by `admin` on `Wed Apr 02 09:59:51 GMT 2025`
Record UNII	9E96TNX6EZ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NSC-172131

Preferred Name

English

FENHARMANE

Official Name

English

1-BENZYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO(3,4-B)INDOLE

Systematic Name

English

fenharmane [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28197

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

Code System Code Type Description

CAS

3851-30-7

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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EVMPD

SUB07564MIG

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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ChEMBL

CHEMBL2106159

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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EPA CompTox

DTXSID101043296

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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PUBCHEM

71167

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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INN

1780

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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FDA UNII

9E96TNX6EZ

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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NSC

172131

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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NCI_THESAURUS

C65650

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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SMS_ID

100000081275

Created by admin on Wed Apr 02 09:59:51 GMT 2025 , Edited by admin on Wed Apr 02 09:59:51 GMT 2025

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