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Details

Stereochemistry ACHIRAL
Molecular Formula C16H10
Molecular Weight 202.2506
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PYRENE

SMILES

C1=CC2=C3C(C=CC4=CC=CC(C=C2)=C34)=C1

InChI

InChIKey=BBEAQIROQSPTKN-UHFFFAOYSA-N
InChI=1S/C16H10/c1-3-11-7-9-13-5-2-6-14-10-8-12(4-1)15(11)16(13)14/h1-10H

HIDE SMILES / InChI

Molecular Formula C16H10
Molecular Weight 202.2506
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Pyrene is a polycyclic aromatic hydrocarbon. Pyrene is a carcinogenic agent and is absorbed by the skin. It is a skin irritant, a suspected mutagen, and an equivocal tumor-causing agent. Pyrene (Py) and various metabolites with a Py chromophore are powerful probes often used in biophysical and biochemical sciences due to their high fluorescent quantum yields and relatively long fluorescence lifetimes. Bioaccumulation of this chemical may occur in crustacea, fish, milk, algae and molluscs.

CNS Activity

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
A bacterium isolated an asphalt plant soil and identified as a strain of Bacillus lentus was tested in vitro and in sterilized and native soils for the ability to survive and sustain pyrene degradation over a period of 63 days. The exponential growth rate in vitro was 0.049 d-1 and the doubling time 2.65 d. In the control flask without pyrene organism density remained virtually constant. In sterilized soil seeded with Bacillus lentus LP32 pyrene concentration declined from 335.0 mg/kg to 8.56 mg/kg at the rate of 10.88 mg/kg/day and half-life of 5.67 days. Similarly, in the native soil with organism there was a decline from 305.2 mg/kg to 8.58 mg/kg in 30 days at the rate of 9.89 mg/kg/day and half-life 5.82. The percentage pyrene degraded in both sterilized and native soils were similar, at 97.45 % and 97.19% respectively.
Substance Class Chemical
Record UNII
9E0T7WFW93
Record Status Validated (UNII)
Record Version