Stereochemistry | ACHIRAL |
Molecular Formula | C16H10 |
Molecular Weight | 202.2506 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CC2=C3C(C=CC4=CC=CC(C=C2)=C34)=C1
InChI
InChIKey=BBEAQIROQSPTKN-UHFFFAOYSA-N
InChI=1S/C16H10/c1-3-11-7-9-13-5-2-6-14-10-8-12(4-1)15(11)16(13)14/h1-10H
Molecular Formula | C16H10 |
Molecular Weight | 202.2506 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Pyrene is a polycyclic aromatic hydrocarbon. Pyrene is a carcinogenic agent and is absorbed by the skin. It is a skin irritant, a suspected mutagen, and an equivocal tumor-causing agent. Pyrene (Py) and various metabolites with a Py chromophore are powerful probes often used in biophysical and biochemical sciences due to their high fluorescent quantum yields and relatively long fluorescence lifetimes. Bioaccumulation of this chemical may occur in crustacea, fish, milk, algae and molluscs.
CNS Activity
Originator
Approval Year
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
PubMed
Patents
Sample Use Guides
A bacterium isolated an asphalt plant soil and identified as a strain of Bacillus lentus was tested in vitro and in sterilized and native soils for the ability to survive and sustain pyrene degradation over a period of 63 days. The exponential growth rate in vitro was 0.049 d-1 and the doubling time 2.65 d. In the control flask without pyrene organism density remained virtually constant. In sterilized soil seeded with Bacillus lentus LP32 pyrene concentration declined from 335.0 mg/kg to 8.56 mg/kg at the rate of 10.88 mg/kg/day and half-life of 5.67 days. Similarly, in the native soil with organism there was a decline from 305.2 mg/kg to 8.58 mg/kg in 30 days at the rate of 9.89 mg/kg/day and half-life 5.82. The percentage pyrene degraded in both sterilized and native soils were similar, at 97.45 % and 97.19% respectively.