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Details

Stereochemistry ACHIRAL
Molecular Formula C16H10O
Molecular Weight 218.25
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-HYDROXYPYRENE

SMILES

OC1=C2C=CC3=CC=CC4=CC=C(C=C1)C2=C34

InChI

InChIKey=BIJNHUAPTJVVNQ-UHFFFAOYSA-N
InChI=1S/C16H10O/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,17H

HIDE SMILES / InChI

Molecular Formula C16H10O
Molecular Weight 218.25
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Dietary fibers reduce the urinary excretion of 1-hydroxypyrene following intravenous administration of pyrene.
2004-03
Urinary 1-hydroxypyrene and mutagenicity in bus drivers and mail carriers exposed to urban air pollution in Denmark.
2004-01-10
Urinary 1-hydroxypyrene as an indicator for assessing the exposures of booth attendants of a highway toll station to polycyclic aromatic hydrocarbons.
2004-01-01
Urinary hydroxy-metabolites of naphthalene, phenanthrene and pyrene as markers of exposure to diesel exhaust.
2004-01
Monitoring internal exposure to metals and organic substances in workers at a hazardous waste incinerator after 3 years of operation.
2003-12-15
r-1,t-2,3,c-4-Tetrahydroxy-1,2,3,4-tetrahydrophenanthrene in human urine: a potential biomarker for assessing polycyclic aromatic hydrocarbon metabolic activation.
2003-12
Synchronous fluorescence spectrometry of 1-hydroxypyrene: a rapid screening method for identification of PAH exposure in tissue from marine polychaetes.
2003-12
Linking exposure to environmental pollutants with biological effects.
2003-11
Solvent effect on cDNA-expressed human sulfotransferase (SULT) activities in vitro.
2003-11
Air concentrations and urinary metabolites of polycyclic aromatic hydrocarbons among paving and remixing workers.
2003-10
Validation of multimedia models assessing exposure to PAHs--the SOLEX study.
2003-10
Influence of genetic polymorphisms of CYP1A1 and GSTM1 on the urinary levels of 1-hydroxypyrene.
2003-09-15
Susceptibility and exposure biomarkers in people exposed to PAHs from diesel exhaust.
2003-09-15
[A study on the relationship between urinary 1-hydroxypyrene level and early genetic effect among coke oven workers].
2003-09
Natural gas and indoor air pollution: a comparison with coal gas and liquefied petroleum gas.
2003-09
1-Hydroxypyrene as a biomarker for fish exposure to polycyclic aromatic hydrocarbons.
2003-09
Leukocyte 8-hydroxydeoxyguanosine and aromatic DNA adduct in coke-oven workers with polycyclic aromatic hydrocarbon exposure.
2003-09
Fast and sensitive determination of urinary 1-hydroxypyrene by packed capillary column switching liquid chromatography coupled to micro-electrospray time-of-flight mass spectrometry.
2003-08-25
Oxidative DNA damage estimated by urinary 8-hydroxydeoxyguanosine: influence of taxi driving, smoking and areca chewing.
2003-08
DNA damage in T- and B-lymphocytes and granulocytes in emission inspection and incineration workers exposed to polycyclic aromatic hydrocarbons.
2003-07-08
Monitoring human occupational and environmental exposures to polycyclic aromatic compounds.
2003-07
Pyrene metabolism in the springtail Orchesella cincta L. (Collembola, Entomobryidae).
2003-07
Detection of 1-hydroxypyrene in urine by direct fluorometric analysis on a solid sorbing phase. Validation and application of the method to biological monitoring of PAH-exposed persons.
2003-07
Occupational exposure to bitumen during road paving.
2003-06-21
Polyaromatic hydrocarbons administered in humans by dermal route increase total IgE.
2003-06-12
The application of HPLC-F and GC-MS to the analysis of selected hydroxy polycyclic hydrocarbons in two certified fish bile reference materials.
2003-06
Genetic effects on urinary 1-hydroxypyrene levels in a Korean population.
2003-06
Simultaneous determination of urinary 1- and 2-naphthols, 3- and 9-phenanthrols, and 1-pyrenol in coke oven workers.
2003-05-31
Effects of genetic polymorphisms in metabolic enzymes on the relationships between 8-hydroxydeoxyguanosine levels in human leukocytes and urinary 1-hydroxypyrene and 2-naphthol concentrations.
2003-05
1-Hydroxypyrene glucuronide as the major aqueous pyrene metabolite in tissue and gut fluid from the marine deposit-feeding polychaete Nereis diversicolor.
2003-05
[Environmental and biological reference values of aromatic polycyclic hydrocarbons].
2003-04-17
Simultaneous analysis of naphthols, phenanthrols, and 1-hydroxypyrene in urine as biomarkers of polycyclic aromatic hydrocarbon exposure: intraindividual variance in the urinary metabolite excretion profiles caused by intervention with beta-naphthoflavone induction in the rat.
2003-04
Exposure to environmental tobacco smoke and urinary 1-hydroxypyrene levels in preschool children.
2003-03
Personal exposure to PM2.5 and biomarkers of DNA damage.
2003-03
Correlation of urinary 1-hydroxypyrene and 2-naphthol with total suspended particulates in ambient air in municipal middle-school students in Korea.
2003-01-18
Urinary 1-hydroxypyrene levels in workers exposed to coke oven emissions at various locations in a coke oven plant.
2003-01-01
Method for determining monohydroxybenzo[a]pyrene isomers using column-switching high-performance liquid chromatography.
2003-01-01
Pyrene biotransformation products as biomarkers of polycyclic aromatic hydrocarbon exposure in terrestrial Isopoda: concentration-response relationship, and field study in a contaminated forest.
2003-01
Screening pyrene metabolites in the hemolymph of dungeness crabs (Cancer magister) with synchronous fluorescence spectrometry: method development and application.
2003-01
Sources of polycyclic aromatic hydrocarbon exposure in non-occupationally exposed Koreans.
2003
Urinary excretion of 8-hydroxy-2-deoxyguanosine and 1-hydroxypyrene in coke-oven workers.
2003
1-hydroxypyrene as a biomarker of occupational exposure to polycyclic aromatic hydrocarbons (PAH) in boilermakers.
2002-12
Tobacco-smoke exposure indicators and urinary mutagenicity.
2002-11-26
Is 1-hydroxypyrene a reliable bioindicator of measured dietary polycyclic aromatic hydrocarbon under normal conditions?
2002-10-05
Determination of selected monohydroxy metabolites of 2-, 3- and 4-ring polycyclic aromatic hydrocarbons in urine by solid-phase microextraction and isotope dilution gas chromatography-mass spectrometry.
2002-10-05
Biomonitoring of polycyclic aromatic hydrocarbons in human urine.
2002-10-05
Metabolism of pyrene by two clam species, Mya arenaria and Protothaca staminea.
2002-10
Direct determination of 1-hydroxypyrene in fish from coastal water by synchronous fluorimetry.
2002-10
Cytochrome P450 1B1 mRNA levels in peripheral blood cells and exposure to polycyclic aromatic hydrocarbons in Chinese coke oven workers.
2002-09-16
The photophysics of 1-hydroxypyrene, the acidity of its singlet excited state, and the nature of its photoionization process in polar media.
2002-02
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 19:51:49 GMT 2025
Edited
by admin
on Mon Mar 31 19:51:49 GMT 2025
Record UNII
N2H6O5V707
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1-HYDROXYPYRENE
Systematic Name English
NSC-30968
Preferred Name English
3-HYDROXYPYRENE
Systematic Name English
PYREN-1-OL
Systematic Name English
1-PYRENOL
Systematic Name English
Code System Code Type Description
MESH
C033146
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
FDA UNII
N2H6O5V707
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
EPA CompTox
DTXSID1038298
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
PUBCHEM
21387
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
CAS
5315-79-7
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
NSC
30968
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
WIKIPEDIA
1-Hydroxypyrene
Created by admin on Mon Mar 31 19:51:49 GMT 2025 , Edited by admin on Mon Mar 31 19:51:49 GMT 2025
PRIMARY
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