PF-03049423 FREE BASE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H32N6O4
Molecular Weight	468.5487
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCOCCN1C(=O)C(=NC2=C1C=C(N=C2)C3=CC=C(OC)N=C3)N4CCN(CCO)CC4

InChI

InChIKey=MNLNAGRCHNMKKJ-UHFFFAOYSA-N

InChI=1S/C24H32N6O4/c1-3-13-34-14-11-30-21-15-19(18-4-5-22(33-2)26-16-18)25-17-20(21)27-23(24(30)32)29-8-6-28(7-9-29)10-12-31/h4-5,15-17,31H,3,6-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C24H32N6O4
Molecular Weight	468.5487
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
cGMP-specific 3',5'-cyclic phosphodiesterase 6 Target ID: O76074 Gene ID: 8654.0 Gene Symbol: PDE5A Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/26738812	Inhibitor 8297

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:41:48 UTC 2023` Edited by `admin` on `Sat Dec 16 01:41:48 UTC 2023`
Record UNII	9CZX3Z9945
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PF-03049423 FREE BASE

Code

English

PF-5

Code

English

PYRIDO(3,4-B)PYRAZIN-2(1H)-ONE, 3-(4-(2-HYDROXYETHYL)-1-PIPERAZINYL)-7-(6-METHOXY-3-PYRIDINYL)-1-(2-PROPOXYETHYL)-

Systematic Name

English

Code System Code Type Description

SMS_ID

300000042473

Created by admin on Sat Dec 16 01:41:48 UTC 2023 , Edited by admin on Sat Dec 16 01:41:48 UTC 2023

PRIMARY

FDA UNII

9CZX3Z9945

Created by admin on Sat Dec 16 01:41:48 UTC 2023 , Edited by admin on Sat Dec 16 01:41:48 UTC 2023

PRIMARY

PUBCHEM

24963293

Created by admin on Sat Dec 16 01:41:48 UTC 2023 , Edited by admin on Sat Dec 16 01:41:48 UTC 2023

PRIMARY

CAS

954138-07-9

Created by admin on Sat Dec 16 01:41:48 UTC 2023 , Edited by admin on Sat Dec 16 01:41:48 UTC 2023

PRIMARY

Related Record Type Details


					9CZX3Z9945

PF-03049423 FREE BASE

ACTIVE MOIETY

Comments:

Drugs: Bupivacaine(Primary), Epinephrine, Ketorolac, Morphine, Ropivacaine, Sodium chloride; Indication: Postoperative pain; Focus: Therapeutic Use; Most Recent Event: 28 Nov 2014 New trial record