0.5 g 3 times a day. The maximum single dose is 1 g, daily - 2 g. Treatment begins when the first signs of the disease appear. The recommended course of treatment is 5 to 7 days.

MatTeks’s EpiAirway System (MatTek, Ashland, MA) differentiated normal human-derived bronchial epithelial cells (NHBE) were used for the study. The cells from a single donor were used for assay consistency. The apical surface of the cells was exposed to a humidified 95% air/5% CO2 environment and the basolateral medium changed and mucin washed every 24-48 hours. NHBE cells were inoculated with influenza A viruses by exposure of the apical side to influenza virus. After a 1-hour incubation, the viral inoculum was removed from the cells, the apical side of the cells washed with Phosphate Buffered Saline (PBS). For the positive control, oseltamivir carboxylate, NHBE cultures were exposed on the basal side to oseltamivir for 60 minutes, prior to viral inoculation. Enisamium (40-1000mkM) or control media was added to the in the basal media compartment of the NHBE culture system prior to or post inoculation and incubated for the indicated duration of the experiment.