SULFACHLORPYRAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H9ClN4O2S
Molecular Weight	284.722
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=CC=C(C=C1)S(=O)(=O)NC2=NC=C(Cl)N=C2

InChI

InChIKey=GDANWVKBBCWCIJ-UHFFFAOYSA-N

InChI=1S/C10H9ClN4O2S/c11-9-5-14-10(6-13-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C10H9ClN4O2S
Molecular Weight	284.722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23682263 | https://www.jstage.jst.go.jp/article/jpsa1964/11/3/11_3_75/_pdf

Sulfachloropyrazine, a sulfonamide, was developed as a drug for poultry coccidiosis. Sulfachloropyrazine was found to be a therapeutic option for T. gondii infection in animals.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Coccidiosis 45 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4805788 https://www.ncbi.nlm.nih.gov/pubmed/2583024 http://agris.fao.org/agris-search/search.do?recordID=PL8301030 http://www-staro.vef.unizg.hr/vetarhiv/papers/2013-83-2-9.pdf	Curative		Approved 8583	SULFATYF Approved Use Poultry coccidiosis
Toxoplasmosis 13 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23569838 https://www.ncbi.nlm.nih.gov/pubmed/23682263	Curative		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Comparative studies on the efficacy of sulphachlorpyrazine and toltrazuril for the treatment of caecal coccidiosis in chickens.	1995-06	7657461
[The compatibility of the new ionophore-coccidiostats with other chemotherapeutics in broilers].	1989-10	2583024
[Effectiveness of sulfachlorpyrazine in coccidiosis of rabbits].	1973-04	4805788

Patents

Sample Use Guides

In Vivo Use Guide

chicken and turkey: 0.03% sulfachlorpyrazine solution as source of water for 3 days.

Route of Administration: Oral

In Vitro Use Guide

T. gondii tachyzoites were soaked in sulfachloropyrazine (250 mg/mL) for 2 h at 37 °C.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:55:37 GMT 2025` Edited by `admin` on `Mon Mar 31 19:55:37 GMT 2025`
Record UNII	96R84UZ2XA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFACHLORPYRAZINE

Common Name

English

4-AMINO-N-(5-CHLOROPYRAZINYL)-BENZENESULFONAMIDE

Preferred Name

English

BENZENESULFONAMIDE, 4-AMINO-N-(5-CHLORO-2-PYRAZINYL)-

Systematic Name

English

BENZENESULFONAMIDE, 4-AMINO-N-(5-CHLOROPYRAZINYL)-

Systematic Name

English

Code System Code Type Description

CAS

1672-91-9