ZINC SALICYLATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C7H5O3.Zn
Molecular Weight	339.635
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Zn++].OC1=CC=CC=C1C([O-])=O.OC2=CC=CC=C2C([O-])=O

InChI

InChIKey=PZXFWBWBWODQCS-UHFFFAOYSA-L

InChI=1S/2C7H6O3.Zn/c2*8-6-4-2-1-3-5(6)7(9)10;/h2*1-4,8H,(H,9,10);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	C7H5O3
Molecular Weight	137.1128
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Zn
Molecular Weight	65.409
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.vertellus.com/products/personal-consumer-care/salts/zinc-salicylate | https://www.ducray.com/en-gb/node/67090

Zinc Salicylate is an antiseptic, astringent and source of zinc for personal care products such as dusting powders and antiperspirants. It is also used in the production of carbonless copy paper as a color developer.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Acne-prone skin 1 Sources: https://www.ducray.com/en-gb/node/67090 https://www.ducray.com/en-gb/node/67087	Curative		Approved 8429	KERACNYL Approved Use Zinc salicylate as a component of cosmetic products for acne-prone skin

PubMed

Title	Date	PubMed
Extraction and determination of zinc in pharmaceutical samples.	1989 Apr	18964740
An evaluation of retrograde tracing methods for the identification of chemically distinct cochlear efferent neurons.	1990 Jul	1702612
Oral administration of Bis(aspirinato)zinc(II) complex ameliorates hyperglycemia and metabolic syndrome-like disorders in spontaneously diabetic KK-A(y) mice: structure-activity relationship on zinc-salicylate complexes.	2011	21804241
The application of bioactive compounds from the food industry to control mold growth in indoor waterborne coatings.	2013 Apr 1	23298599

Patents

Sample Use Guides

In Vivo Use Guide

Mice were treated with Zn(sal)2 at the dose of 15 mg Zn/kg body weight for 24 d by daily oral administrations. Zinc salicylate is a component of cosmetic products for acne-prone skin applying once or twice a day.

Route of Administration: Other

In Vitro Use Guide

Zn(sal)2 exerts insulinomimetic activity in the free fatty acids release from isolated rat adipocytes (IC50 1 mM)

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:09:57 GMT 2023` Edited by `admin` on `Fri Dec 15 19:09:57 GMT 2023`
Record UNII	96OQ2F972S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZINC SALICYLATE

Official Name

English

ZINC SALICYLATE [MI]

Common Name

English

ZINC, BIS(SALICYLATO)-

Common Name

English

Zinc Salicylate [WHO-DD]

Common Name

English

BENZOIC ACID, 2-HYDROXY-, ZINC SALT (2:1)

Common Name

English

ZINC, BIS(2-(HYDROXY-.KAPPA.O)BENZOATO-.KAPPA.O)-, (T-4)-

Common Name

English

ZINC SALICYLATE [INCI]

Common Name

English

ZINC, BIS(2-HYDROXYBENZOATO-O1,O2)-, (.BETA.-4)-

Common Name

English

ZINC BIS(2-HYDROXYBENZOATE)

Systematic Name

English

E 304

Common Name

English

ZINC DISALICYLATE

Systematic Name

English

Code System Code Type Description

FDA UNII

96OQ2F972S