IOFORMINOL

Investigational

Details

Stereochemistry	MIXED
Molecular Formula	C33H40I6N6O15
Molecular Weight	1522.1287
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCC(O)CNC(=O)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(N(CC(O)CN(C=O)C2=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C2I)C=O)=C1I

InChI

InChIKey=BFVVDRUCXCIALU-UHFFFAOYSA-N

InChI=1S/C33H40I6N6O15/c34-22-18(30(57)40-1-13(52)7-46)24(36)28(25(37)19(22)31(58)41-2-14(53)8-47)44(11-50)5-17(56)6-45(12-51)29-26(38)20(32(59)42-3-15(54)9-48)23(35)21(27(29)39)33(60)43-4-16(55)10-49/h11-17,46-49,52-56H,1-10H2,(H,40,57)(H,41,58)(H,42,59)(H,43,60)

HIDE SMILES / InChI

Molecular Formula	C33H40I6N6O15
Molecular Weight	1522.1287
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/20849319 | https://www.ncbi.nlm.nih.gov/pubmed/20799918

Ioforminol is a triiodobenzenedicarboxamide derivative patented by Ge Healthcare A/S as diagnostic agent for X-ray imaging. The toxicity and biodistribution properties of Ioforminol are similar to those of other radiographic contrast media. However, the osmolality of Ioforminol solutions is considerably lower than that of other dimeric radiographic contrast media, thus allowing for an iso-osmolar formulation containing a high concentration of electrolytes. Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH

Originator

Approval Year

PubMed

Title	Date	PubMed
Predicting cardiotoxicity propensity of the novel iodinated contrast medium GE-145: Ventricular fibrillation during left coronary arteriography in pigs.	2010-11	20799918

Patents

Sample Use Guides

In Vivo Use Guide

Iopamidol 300 mgI/mL Given as a single administration to the subject

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:16:51 GMT 2025` Edited by `admin` on `Mon Mar 31 21:16:51 GMT 2025`
Record UNII	95FNF21CDN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ioforminol [INN]

Preferred Name

English

IOFORMINOL

Official Name

English

IOFORMINOL [USAN]

Common Name

English

AN-113111

Code

English

Ioforminol [WHO-DD]

Common Name

English

FEK-256-062

Code

English

1,3-BENZENEDICARBOXAMIDE, 5,5'-((2-HYDROXY-1,3-PROPANEDIYL)BIS(FORMYLIMINO))BIS(N1,N3-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-

Common Name

English

GE-145

Code

English

Code System Code Type Description

INN

9245