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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H16F3N
Molecular Weight 231.2573
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEVOFENFLURAMINE

SMILES

CCN[C@H](C)CC1=CC(=CC=C1)C(F)(F)F

InChI

InChIKey=DBGIVFWFUFKIQN-SECBINFHSA-N
InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1

HIDE SMILES / InChI

Molecular Formula C12H16F3N
Molecular Weight 231.2573
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

LEVOFENFLURAMINE is a levorotatory enantiomer of fenfluramine, a substituted amphetamine which was formerly used to treat obesity. LEVOFENFLURAMINE has dopamine-antagonistic properties and, at high doses, increases dopamine concentrations in rat striatal dialysates. It is essentially inactive to reduce food intake in human subjects.

CNS Activity

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

PubMed

Substance Class Chemical
Record UNII
953A94Y45B
Record Status Validated (UNII)
Record Version