Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H9O2.H4N |
| Molecular Weight | 203.2371 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[NH4+].[O-]C(=O)CC1=C2C=CC=CC2=CC=C1
InChI
InChIKey=DFJCVWWLYPHXNW-UHFFFAOYSA-N
InChI=1S/C12H10O2.H3N/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);1H3
| Molecular Formula | C12H10O2 |
| Molecular Weight | 186.2066 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H3N |
| Molecular Weight | 17.0305 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: http://www.phafag.at/galle-donau-dragees/http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC34404 | https://www.ncbi.nlm.nih.gov/pubmed/26995913https://www.ncbi.nlm.nih.gov/pubmed/603629Curator's Comment: description was created based on several sources, including:
Paranjape, K., Gowariker, V., Krishnamurthy, V.N., Gowariker, S. (2014) "The Pesticide Encyclopedia", p.319 Retrieved from https://books.google.ru/books?id=cnDHBgAAQBAJ
Sources: http://www.phafag.at/galle-donau-dragees/http://www.pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC34404 | https://www.ncbi.nlm.nih.gov/pubmed/26995913https://www.ncbi.nlm.nih.gov/pubmed/603629
Curator's Comment: description was created based on several sources, including:
Paranjape, K., Gowariker, V., Krishnamurthy, V.N., Gowariker, S. (2014) "The Pesticide Encyclopedia", p.319 Retrieved from https://books.google.ru/books?id=cnDHBgAAQBAJ
1-Naphthyl acetate may be used in a rapid staining method for identification of macrophages. And it was used as a susbtrate for different type of esterases, e.g. butyrylcholinesterase, α-naphthyl acetate esterase for determination of their properties towards to insecticide resistance.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: horse butyrylcholinesteras |
|||
Target ID: α-naphthyl acetate esterase |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | Galle-Donau Approved UseGALLE-DONAU - Dragees are used to treat Bile deposits and functional disorders of the gall bladder and bile ducts without organic causes. Launch Date1962 |
|||
| Primary | Galle-Donau Approved UseGALLE-DONAU - Dragees are used to treat Bile deposits and functional disorders of the gall bladder and bile ducts without organic causes. Launch Date1962 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Method for the Quantitative Determination of 1-Naphthaleneacetic Acid in Spiked Canned Pineapple Samples by Micelle-Stabilized Room Temperature Phosphorescence. | 1998 Feb 16 |
|
| Purification and characterization of trans-permethrin metabolizing microsomal esterases from workers of the eastern subterranean termite, Reticulitermes flavipes (Kollar). | 2001 Apr 27 |
|
| Auxin is a positive regulator for ethylene-mediated response in the growth of Arabidopsis roots. | 2001 Mar |
|
| Determination of photophysical rate constants for the non-protected fluid room temperature phosphorescence of several naphthalene derivatives. | 2001 May |
|
| Regulation of rat carboxylesterase expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): a dose-dependent decrease in mRNA levels but a biphasic change in protein levels and activity. | 2001 Nov |
|
| Ion fluxes, auxin and the induction of elongation growth in Nicotiana tabacum cells. | 2001 Nov |
|
| Effect of top excision and replacement by 1-naphthylacetic acid on partition and flow of potassium in tobacco plants. | 2001 Nov |
|
| Hematology, morphology, cytochemical staining, and ultrastuctural characteristics of blood cells in king cobras (Ophiophagus hannah). | 2002 |
|
| Resistance of aphis gossypii (Homoptera: Aphididae) to fenvalerate and imidacloprid and activities of detoxification enzymes on cotton and cucumber. | 2002 Apr |
|
| Resistance of transgenic tobacco seedlings expressing the Agrobacterium tumefaciens C58-6b gene, to growth-inhibitory levels of cytokinin is associated with elevated IAA levels and activation of phenylpropanoid metabolism. | 2002 Aug |
|
| Identification and quantification of polar naphthalene derivatives in contaminated groundwater of a former gas plant site by liquid chromatography-electrospray ionization tandem mass spectrometry. | 2002 Aug 23 |
|
| In vitro regeneration of roots of Phyla nodiflora and Leptadenia reticulata, and comparison of roots from cultured and natural plants for secondary metabolites. | 2002 Dec |
|
| Auxin efflux carrier activity and auxin accumulation regulate cell division and polarity in tobacco cells. | 2002 Dec |
|
| Involvement of diverse protein kinase C isoforms in the differentiation of ML-1 human myeloblastic leukemia cells induced by the vitamin D3 analogue KH1060 and the phorbol ester TPA. | 2002 Dec 1 |
|
| A rapid TLC bioautographic method for the detection of acetylcholinesterase and butyrylcholinesterase inhibitors in plants. | 2002 Jan-Feb |
|
| AUX1 promotes lateral root formation by facilitating indole-3-acetic acid distribution between sink and source tissues in the Arabidopsis seedling. | 2002 Mar |
|
| [Production of regenerants in sugar beet]. | 2002 May-Jun |
|
| On the mechanism of selectivity of the corn herbicide BAS 662H: a combination of the novel auxin transport inhibitor diflufenzopyr and the auxin herbicide dicamba. | 2002 Oct |
|
| A preliminary investigation of the role of auxin and cytokinin in sylleptic branching of three hybrid poplar clones exhibiting contrasting degrees of sylleptic branching. | 2002 Sep |
|
| Purification and characterization of a carboxylesterase involved in malathion-specific resistance from Tribolium castaneum (Coleoptera: Tenebrionidae). | 2002 Sep |
|
| Production of ajmalicine and ajmaline in hairy root cultures of Rauvolfia micrantha Hook f., a rare and endemic medicinal plant. | 2003 Apr |
|
| Transgene expression in broccoli (Brassica oleracea var. italica) clones propagated in vitro via leaf explants. | 2003 Apr |
|
| Encapsulation of nodal cuttings and shoot tips for storage and exchange of cassava germplasm. | 2003 Apr |
|
| Direct somatic embryogenesis and synthetic seed production from Paulownia elongata. | 2003 Aug |
|
| Flavonoid-related regulation of auxin accumulation in Agrobacterium tumefaciens-induced plant tumors. | 2003 Dec |
|
| Production of haploids of neem (Azadirachta indica A. Juss.) by anther culture. | 2003 Feb |
|
| Rapid in vitro multiplication and ex vitro rooting of Rotula aquatica Lour., a rare rhoeophytic woody medicinal plant. | 2003 Jan |
|
| Intramolecular excimer formation in a naphthalene-appended dinuclear iron-oxo complex. | 2003 Jan 27 |
|
| Production of alkaloids by in vitro culture of Erythrina americana Miller. | 2003 Jul |
|
| Plant regeneration from callus of apomictic and sexual lines of Paspalum simplex and RFLP analysis of regenerated plants. | 2003 Jul |
|
| [Specific features of the development of Siberian stone pine megagametophytes and embryos in vitro]. | 2003 Jul-Aug |
|
| [Effect of jasminic acid on production of anthracene derivatives in cultures of Rheum palmatum L]. | 2003 May |
|
| Isoenzymes of peroxidase and esterase related to morphogenesis in Mammillaria gracillis Pfeiff. tissue culture. | 2003 Nov |
|
| Characterization of a wound-inducible cytochrome P450 gene ( CYP72A29) that is down-regulated during crown gall tumorigenesis in potato tuber. | 2003 Nov |
|
| Somatic embryogenesis in sisal ( Agave sisalana Perr. ex. Engelm). | 2003 Oct |
|
| Fast kinetic determination of 1-naphthylacetic acid in commercial formulations, soils, and fruit samples using stopped-flow phosphorimetry. | 2003 Oct 22 |
|
| Somatic embryogenesis from leaf explants of Australian fan flower, Scaevola aemula R. Br. | 2004 Jan |
|
| Direct organogenesis of Mandevilla illustris (Vell) Woodson and effects of its aqueous extract on the enzymatic and toxic activities of Crotalus durissus terrificus snake venom. | 2004 Mar |
|
| Transformation of the monocotyledonous Alstroemeria by Agrobacterium tumefaciens. | 2004 Mar |
|
| [Effects of sodium naphthalene acetate on growth and physiological characteristics of tomato seedlings under suboptimal temperature and light condition]. | 2015 Oct |
Patents
Sample Use Guides
1-2 dragees with liquid before each meal. The single dose can be increased to 3-4 dragees.
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:03:57 GMT 2023
by
admin
on
Sat Dec 16 08:03:57 GMT 2023
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| Record UNII |
944RJ2211X
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID2034334
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ammonium 1-naphthaleneacetate
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62796
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25545-89-5
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247-088-9
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944RJ2211X
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