ERBUMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H11N
Molecular Weight	73.1368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)N

InChI

InChIKey=YBRBMKDOPFTVDT-UHFFFAOYSA-N

InChI=1S/C4H11N/c1-4(2,3)5/h5H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C4H11N
Molecular Weight	73.1368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://nj.gov/health/eoh/rtkweb/documents/fs/3025.pdf | https://cameochemicals.noaa.gov/chemical/8358

Erbumine (tert-butylamine) is a colorless liquid with an ammonia-like odor. It is used in the preparation of insecticides, pharmaceuticals, oil additives, and rubber accelerators. It neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Approval Year

PubMed

Title	Date	PubMed
Preparation and root growth-modulatory activity of N-substituted 2-acetylamino-2-ethoxycarbonyl-3-(2-furyl)propanamides.	2001 Mar	11253928
Nucleophilic substitution induced by electron transfer at the bridgehead of polycyclic alkanes: competition between polar and radical pathways.	2001 May 18	11348118
Preparation and characterisation of a range of diclofenac salts.	2001 Sep 11	11532579
Determination of regioselectivity in ring opening of tert-butylaziridinones by a combination of (15)N labeling and electrospray ionization-ion trap mass spectrometry.	2002 Jan	11813308
A piezoelectric quartz crystal sensor array self assembled calixarene bilayers for detection of volatile organic amine in gas.	2002 Jul 19	18968724
The new generation dihydropyridine type calcium blockers, bearing 4-phenyl oxypropanolamine, display alpha-/beta-adrenoceptor antagonist and long-acting antihypertensive activities.	2002 Mar	11814861
Potential bile acid metabolites. 25. Synthesis and chemical properties of stereoisomeric 3alpha,7alpha,16- and 3alpha,7alpha,15-trihydroxy-5beta-cholan-24-oic acids.	2002 Oct	12372858
Ruthenium-catalyzed reaction of alpha,beta-unsaturated imines with carbon monoxide and alkenes leading to beta,gamma-unsaturated gamma-butyrolactams: involvement of direct carbonylation at olefinic C[bond]H Bonds as a key step.	2002 Oct 4	12353994
Intramolecular and intermolecular N-H...C(5)H(5)(-) hydrogen bonding in magnesocene adducts of alkylamines. Implications for chemical vapor deposition using cyclopentadienyl source compounds.	2002 Sep 25	12236729
Transannular reactions of two parallel 1,3-butadiynes: syntheses, structures, and reactions of 1-azacyclotetradeca-3,5,10,12-tetrayne derivatives.	2003 Apr 14	12698439
Cucurbit[6]uril pseudorotaxanes: distinctive gas-phase dissociation and reactivity.	2003 Aug 6	12889944
Application of an alkyl-diol silica precolumn in a column-switching system for the determination of meloxicam in plasma.	2003 Aug 8	12899970
Diminished reactivity of ortho-substituted phenacyl bromides toward nucleophilic displacement.	2003 Feb 21	12585913
Optical sensor for amine vapors based on dimer-monomer equilibrium of indium(III) octaethylporphyrin in a polymeric film.	2003 Jan 15	12553770
Increasing rates and scope of reactions: sluggish amines in microwave-heated aminocarbonylation reactions under air.	2003 Jul 11	12839476
Competing sulfonylation and phosphonylation following rearrangement of an O-sulfonyl-N-phosphinoylhydroxylamine with tert-butylamine: demonstration of a phosphonamidic-sulfonic anhydride intermediate and 18O-labelling evidence on how it may be formed.	2003 Oct 7	14584802
A general study of [(eta5-Cp')2Ti(eta2-Me3SiC2SiMe3)]-catalyzed hydroamination of terminal alkynes: regioselective formation of Markovnikov and anti-Markovnikov products and mechanistic explanation (Cp'=C5H5, C5H4Et, C5Me5).	2004 May 17	15146514
Thiol-reactive clenbuterol analogues conjugated to bovine serum albumin.	2004 Nov-Dec	15666550
An unusual zwitterionic, diradical intermediate in photochemical electron-transfer substitution reactions.	2004 Oct 13	15469246
ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes.	2004 Sep 28	15363507
Enantioselective nitrile anion cyclization to substituted pyrrolidines. A highly efficient synthesis of (3S,4R)-N-tert-butyl-4-arylpyrrolidine-3-carboxylic acid.	2005 Apr 29	15844996
Human erythrocyte delta-aminolevulinate dehydratase inhibition by monosaccharides is not mediated by oxidation of enzyme sulfhydryl groups.	2005 Aug	15950499
Kinetic stability of heteroleptic (beta-diketiminato) heavier alkaline-earth (Ca, Sr, Ba) amides.	2005 Jan 21	15616716
Distribution of amines in water/AOT/n-hexane reverse micelles: influence of the amine chemical structure.	2005 Jun 1	15848423
99mTcN complexes of tert-butyl dithiocarbamate and methoxyisobutyl dithiocarbamate as myocardial and brain imaging agents.	2005 Nov	16208180
Investigation of the electrochemical oxidation products of zotepine and their fragmentation using on-line electrochemistry/electrospray ionization mass spectrometry.	2006 May	16575780
Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile.	2008 Dec 26	18948265
Synthesis and evaluation of L-glutamic Acid analogs as potential anticancer agents.	2008 Mar-Apr	20046724
The use of microcalorimetry and HPLC for the determination of degradation kinetics and thermodynamic parameters of Perindopril Erbumine in aqueous solutions.	2008 May 22	18304767
Isolation and characterization of a neutral imino-semiquinone radical.	2008 May 7	18402446
Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human beta1-adrenoceptor.	2008 Nov	18687809
tert-Butyl-ammonium 2,3,4,5-tetra-chloro-6-methoxy-carbonyl-benzoate.	2008 Nov 13	21581294
An acyclic dimer of cyclodiphosphazane {(t)BuHN((t)BuNP)2OCH2}2 containing alkoxo and amido functionalities: synthesis, derivatization, Bi- (Pd(II), Rh(I)), and tetranuclear (Pd(II), Au(I), Rh(I)Au(I)) transition metal complexes.	2009 Feb 16	19133774
tert-Butyl-aminium phosphite.	2009 Feb 28	21582288
N,N-Bis(2-pyridylmeth-yl)-tert-butyl-amine.	2009 Jan 28	21581995
Stabilization of quinapril by incorporating hydrogen bonding interactions.	2009 Jul	20502545
Structural transformations of sVI tert-butylamine hydrates to sII binary hydrates with methane.	2009 Oct 22	19780602
Applications of chitin and its derivatives in biological medicine.	2010	21614199
Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile.	2010 Aug 21	20574586
(tert-Butyl-imido)bis-(η-cyclo-penta-dien-yl)pyridine-zirconium(IV).	2010 Aug 28	21588566
Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets.	2010 Dec	20823098
Step-mediated anisotropic adsorption and condensation of tert-butylamine on Cu(111).	2010 Feb 1	20058290
Novel synthesis of ureas: application of t-butylureas.	2010 Jan	20045971
Effect of guest-host hydrogen bonding on the structures and properties of clathrate hydrates.	2010 Jan 18	19946907
"Turn-on" fluorescent polymeric microparticle sensors for the determination of ammonia and amines in the vapor state.	2010 Jun	20498886
2-Methyl-propan-2-aminium 4-hy-droxy-benzoate.	2010 Jun 18	21587926

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:38:57 GMT 2023` Edited by `admin` on `Fri Dec 15 18:38:57 GMT 2023`
Record UNII	91Z53KF68U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ERBUMINE

Official Name

English

2-METHYLPROPAN-2-AMINE

Systematic Name

English

1,1-DIMETHYLETHYLAMINE

Systematic Name

English

NSC-9571

Code

English

T-BUTYLAMINE

Common Name

English

TERT-BUTYLAMINE

Systematic Name

English

TERT-BUTYLAMINE [MI]

Common Name

English

2-PROPANAMINE, 2-METHYL-

Common Name

English

BUTYLAMINE, TERT-

Systematic Name

English

erbumine [INN]

Common Name

English

2-METHYL-2-PROPANAMINE [HSDB]

Common Name

English

Code System Code Type Description

NSC

9571