Erbumine

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H11N
Molecular Weight	73.1368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)N

InChI

InChIKey=YBRBMKDOPFTVDT-UHFFFAOYSA-N

InChI=1S/C4H11N/c1-4(2,3)5/h5H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C4H11N
Molecular Weight	73.1368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://nj.gov/health/eoh/rtkweb/documents/fs/3025.pdf | https://cameochemicals.noaa.gov/chemical/8358

Erbumine (tert-butylamine) is a colorless liquid with an ammonia-like odor. It is used in the preparation of insecticides, pharmaceuticals, oil additives, and rubber accelerators. It neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Approval Year

PubMed

Title	Date	PubMed
Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets.	2010-12	20823098
(tert-Butyl-imido)bis-(η-cyclo-penta-dien-yl)pyridine-zirconium(IV).	2010-08-28	21588566
Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile.	2010-08-21	20574586
2-Methyl-propan-2-aminium 4-hy-droxy-benzoate.	2010-06-18	21587926
"Turn-on" fluorescent polymeric microparticle sensors for the determination of ammonia and amines in the vapor state.	2010-06	20498886
Preparation of N-acetyl, tert-butyl amide derivatives of the 20 natural amino acids.	2010-03	19333720
Step-mediated anisotropic adsorption and condensation of tert-butylamine on Cu(111).	2010-02-01	20058290
Effect of guest-host hydrogen bonding on the structures and properties of clathrate hydrates.	2010-01-18	19946907
Novel synthesis of ureas: application of t-butylureas.	2010-01	20045971
Applications of chitin and its derivatives in biological medicine.	2010	21614199
Structural transformations of sVI tert-butylamine hydrates to sII binary hydrates with methane.	2009-10-22	19780602
Synthesis, crystal structure and spectroscopic properties of a novel carbacylamidophosphate: N-(3-nitrobenzoyl)-N',N''-bis(tert-butyl)phosphoric triamide.	2009-08	19617686
Stabilization of quinapril by incorporating hydrogen bonding interactions.	2009-07	20502545
Titanium hydroamination catalysts bearing a 2-aminopyrrolinato spectator ligand: monitoring the individual reaction steps.	2009-06-21	19488458
Hydrogen storage in double clathrates with tert-butylamine.	2009-06-18	19459664
tert-Butyl-aminium phosphite.	2009-02-28	21582288
An acyclic dimer of cyclodiphosphazane {(t)BuHN((t)BuNP)2OCH2}2 containing alkoxo and amido functionalities: synthesis, derivatization, Bi- (Pd(II), Rh(I)), and tetranuclear (Pd(II), Au(I), Rh(I)Au(I)) transition metal complexes.	2009-02-16	19133774
One ring to bind them all: shape-selective complexation of phenylenediamine isomers with cucurbit[6]uril in the gas phase.	2009-02-12	19146442
N,N-Bis(2-pyridylmeth-yl)-tert-butyl-amine.	2009-01-28	21581995
Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile.	2008-12-26	18948265
tert-Butyl-ammonium 2,3,4,5-tetra-chloro-6-methoxy-carbonyl-benzoate.	2008-11-13	21581294
Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human beta1-adrenoceptor.	2008-11	18687809
Formation of an exciplex with mixed ligands in the mercury-photosensitized luminescence of alcohol-amine mixtures in the liquid phase.	2008-07	17804285
The use of microcalorimetry and HPLC for the determination of degradation kinetics and thermodynamic parameters of Perindopril Erbumine in aqueous solutions.	2008-05-22	18304767
Isolation and characterization of a neutral imino-semiquinone radical.	2008-05-07	18402446
The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues.	2008-04-09	18309292
Evaluation of impurities level of perindopril tert-butylamine in tablets.	2007-09-03	17590561
Synthesis and evaluation of L-glutamic Acid analogs as potential anticancer agents.	2007-03-28	20046724
The formation of endo-complexes between calixarenes and amines--a reinvestigation.	2006-07	16583198
Dynamics of an [Fe4S4(SPh)4]2- cluster explored via IR, Raman, and nuclear resonance vibrational spectroscopy (NRVS)-analysis using 36S substitution, DFT calculations, and empirical force fields.	2006-05-14	16673033
Investigation of the electrochemical oxidation products of zotepine and their fragmentation using on-line electrochemistry/electrospray ionization mass spectrometry.	2006-05	16575780
Dizinc alkoxides and amides supported by binucleating bis(amidoamine) ligands.	2006-02-20	16471998
Structural transition and tuning of tert-butylamine hydrate.	2005-12-02	16252299
99mTcN complexes of tert-butyl dithiocarbamate and methoxyisobutyl dithiocarbamate as myocardial and brain imaging agents.	2005-11	16208180
Human erythrocyte delta-aminolevulinate dehydratase inhibition by monosaccharides is not mediated by oxidation of enzyme sulfhydryl groups.	2005-08	15950499
Distribution of amines in water/AOT/n-hexane reverse micelles: influence of the amine chemical structure.	2005-06-01	15848423
Enantioselective nitrile anion cyclization to substituted pyrrolidines. A highly efficient synthesis of (3S,4R)-N-tert-butyl-4-arylpyrrolidine-3-carboxylic acid.	2005-04-29	15844996
Thiol-reactive clenbuterol analogues conjugated to bovine serum albumin.	2005-01-26	15666550
Kinetic stability of heteroleptic (beta-diketiminato) heavier alkaline-earth (Ca, Sr, Ba) amides.	2005-01-21	15616716
An unusual zwitterionic, diradical intermediate in photochemical electron-transfer substitution reactions.	2004-10-13	15469246
ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes.	2004-09-28	15363507
A general study of [(eta5-Cp')2Ti(eta2-Me3SiC2SiMe3)]-catalyzed hydroamination of terminal alkynes: regioselective formation of Markovnikov and anti-Markovnikov products and mechanistic explanation (Cp'=C5H5, C5H4Et, C5Me5).	2004-05-17	15146514
Competing sulfonylation and phosphonylation following rearrangement of an O-sulfonyl-N-phosphinoylhydroxylamine with tert-butylamine: demonstration of a phosphonamidic-sulfonic anhydride intermediate and 18O-labelling evidence on how it may be formed.	2003-10-07	14584802
Application of an alkyl-diol silica precolumn in a column-switching system for the determination of meloxicam in plasma.	2003-08-08	12899970
Cucurbit[6]uril pseudorotaxanes: distinctive gas-phase dissociation and reactivity.	2003-08-06	12889944
Increasing rates and scope of reactions: sluggish amines in microwave-heated aminocarbonylation reactions under air.	2003-07-11	12839476
Transannular reactions of two parallel 1,3-butadiynes: syntheses, structures, and reactions of 1-azacyclotetradeca-3,5,10,12-tetrayne derivatives.	2003-04-14	12698439
Diminished reactivity of ortho-substituted phenacyl bromides toward nucleophilic displacement.	2003-02-21	12585913
Optical sensor for amine vapors based on dimer-monomer equilibrium of indium(III) octaethylporphyrin in a polymeric film.	2003-01-15	12553770
A piezoelectric quartz crystal sensor array self assembled calixarene bilayers for detection of volatile organic amine in gas.	2002-07-19	18968724

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:17:58 GMT 2025` Edited by `admin` on `Mon Mar 31 19:17:58 GMT 2025`
Record UNII	91Z53KF68U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Erbumine

Official Name

English

TERT-BUTYLAMINE

Preferred Name

English

2-METHYLPROPAN-2-AMINE

Systematic Name

English

1,1-DIMETHYLETHYLAMINE

Systematic Name

English

NSC-9571

Code

English

T-BUTYLAMINE

Common Name

English

TERT-BUTYLAMINE [MI]

Common Name

English

2-PROPANAMINE, 2-METHYL-

Common Name

English

BUTYLAMINE, TERT-

Systematic Name

English

erbumine [INN]

Common Name

English

2-METHYL-2-PROPANAMINE [HSDB]

Common Name

English

Code System Code Type Description

NSC

9571