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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H36O5
Molecular Weight 428.561
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DOMOPREDNATE

SMILES

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CCC[C@]4(OC(=O)CCC)C(C)=O

InChI

InChIKey=IYBYNRHXGXDDDS-VRRJBYJJSA-N
InChI=1S/C26H36O5/c1-5-7-22(30)31-26(16(2)27)12-6-8-20-19-10-9-17-14-18(28)11-13-24(17,3)23(19)21(29)15-25(20,26)4/h11,13-14,19-21,23,29H,5-10,12,15H2,1-4H3/t19-,20-,21-,23+,24-,25-,26-/m0/s1

HIDE SMILES / InChI

Molecular Formula C26H36O5
Molecular Weight 428.561
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Domoprednate is a corticosteroid, a glucocorticoid, with anti-inflammatory and anti-allergic properties. Domoprednate is inferior to betamethasone valerate in the same category of dermatoses and equally well tolerated. It can be characterized as a medium-active corticosteroid. Domoprednate can be used topically in the treatment of skin disorders, such as eczema, psoriasis and atopic dermatitis.

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
The 0.1% ointment was applied twice daily for 4 weeks.
Route of Administration: Topical
Substance Class Chemical
Record UNII
910G0QIM2M
Record Status Validated (UNII)
Record Version