Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2Na.AsHO4.7H2O |
| Molecular Weight | 312.0136 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.O.O.O.O.O.[Na+].[Na+].O[As]([O-])([O-])=O
InChI
InChIKey=KOLXPEJIBITWIQ-UHFFFAOYSA-L
InChI=1S/AsH3O4.2Na.7H2O/c2-1(3,4)5;;;;;;;;;/h(H3,2,3,4,5);;;7*1H2/q;2*+1;;;;;;;/p-2
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | AsH3O4 |
| Molecular Weight | 141.943 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein. | 2015-03-18 |
|
| Monomethylarsenic diglutathione transport by the human multidrug resistance protein 1 (MRP1/ABCC1). | 2011-12 |
|
| Fast, quantitative in situ hybridization of rare mRNAs using 14C-standards and phosphorus imaging. | 2009-12-15 |
|
| Effects of different inorganic arsenic species in Cyprinus carpio (Cyprinidae) tissues after short-time exposure: bioaccumulation, biotransformation and biological responses. | 2009-12 |
|
| Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate. | 2009-10 |
|
| Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase. | 2009-09-01 |
|
| Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols. | 2009-08 |
|
| Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell. | 2009-06-01 |
|
| Effects of inorganic arsenic on the rat and mouse urinary bladder. | 2008-12 |
|
| Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile. | 2008-10-01 |
|
| Arsenite-induced cytotoxicity in dorsal root ganglion explants. | 2008-04-15 |
|
| High dietary fat exacerbates arsenic-induced liver fibrosis in mice. | 2008-03 |
|
| Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis. | 2007-11 |
|
| Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors. | 2007-11 |
|
| Redox regulation of RhoA. | 2006-12-05 |
|
| Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration. | 2006-11-01 |
|
| Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells. | 2006-07 |
|
| Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children. | 2005-06 |
|
| Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine. | 2004-12 |
|
| Regulation of cytoplasmic stress granules by apoptosis-inducing factor. | 2004-09-01 |
|
| Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains. | 2004-04-13 |
|
| Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA. | 2004-03 |
|
| Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. | 2003-12 |
|
| Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes. | 2003-12 |
|
| Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans. | 2003-08 |
|
| Purine nucleoside phosphorylase as a cytosolic arsenate reductase. | 2002-11 |
|
| Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices. | 1999-07 |
|
| Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms. | 1998-04 |
|
| Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression. | 1996-11-01 |
|
| Screening for reproductive toxicity in Fundulus heteroclitus by genetic expression profiling. | 1996 |
|
| Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. | 1994-11-15 |
Patents
| Substance Class |
Chemical
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by
admin
on
Edited
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| Record UNII |
90ZQ7G407W
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Validated (UNII)
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PRIMARY | RxNorm |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ANHYDROUS->SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
