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Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.AsHO4
Molecular Weight 185.9067
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ARSENATE, DIBASIC

SMILES

[Na+].[Na+].O[As]([O-])([O-])=O

InChI

InChIKey=IHZDYHDJAVUIBH-UHFFFAOYSA-L
InChI=1S/AsH3O4.2Na/c2-1(3,4)5;;/h(H3,2,3,4,5);;/q;2*+1/p-2

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula AsHO4
Molecular Weight 139.9271
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ammonium dihydrogen arsenate is an inorganic compound that has been considered a potential electro-optic material and has been explored by a number of investigators for modulation purposes. Ammonium arsenate is a cancerogenic substance.

Approval Year

1921
1468
PubMed

PubMed

TitleDatePubMed
Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein.
2015-03-18
Monomethylarsenic diglutathione transport by the human multidrug resistance protein 1 (MRP1/ABCC1).
2011-12
Fast, quantitative in situ hybridization of rare mRNAs using 14C-standards and phosphorus imaging.
2009-12-15
Effects of different inorganic arsenic species in Cyprinus carpio (Cyprinidae) tissues after short-time exposure: bioaccumulation, biotransformation and biological responses.
2009-12
Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate.
2009-10
Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.
2009-09-01
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.
2009-08
Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell.
2009-06-01
Effects of inorganic arsenic on the rat and mouse urinary bladder.
2008-12
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile.
2008-10-01
Arsenite-induced cytotoxicity in dorsal root ganglion explants.
2008-04-15
High dietary fat exacerbates arsenic-induced liver fibrosis in mice.
2008-03
Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.
2007-11
Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors.
2007-11
Redox regulation of RhoA.
2006-12-05
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration.
2006-11-01
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.
2006-07
Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children.
2005-06
Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine.
2004-12
Regulation of cytoplasmic stress granules by apoptosis-inducing factor.
2004-09-01
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.
2004-04-13
Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA.
2004-03
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
2003-12
Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes.
2003-12
Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans.
2003-08
Purine nucleoside phosphorylase as a cytosolic arsenate reductase.
2002-11
Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices.
1999-07
Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms.
1998-04
Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression.
1996-11-01
Screening for reproductive toxicity in Fundulus heteroclitus by genetic expression profiling.
1996
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
1994-11-15
Patents

Patents

03973022
77
04431807
10
06664111
10
20080041717
10
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:47:15 GMT 2025
Edited
by admin
on Mon Mar 31 17:47:15 GMT 2025
Record UNII
ANU034TUJ4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM ARSENATE, DIBASIC
MI  
Common Name English
DISODIUM ARSENATE
HSDB  
Preferred Name English
ARSENIC ACID SODIUM SALT (1:2)
Common Name English
SODIUM ARSENATE, EXSICCATED
Common Name English
SODIUM ARSENATE [MART.]
Common Name English
ARSENIC ACID (H3ASO4) SODIUM SALT (1:2)
Common Name English
SODIUM ARSENATE, DIBASIC [MI]
Common Name English
DISODIUM ARSENATE [HSDB]
Common Name English
SODIUM ARSENATE, DIBASIC, ANHYDROUS
Common Name English
SODIUM ARSENATE, DIBASIC ANHYDROUS
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID8032047
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
HSDB
1675
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
PUBCHEM
24500
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
MESH
C009277
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
RXCUI
1364793
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY RxNorm
CAS
7778-43-0
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
MERCK INDEX
m9985
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
Disodium hydrogen arsenate
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
ECHA (EC/EINECS)
231-902-4
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
FDA UNII
ANU034TUJ4
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
SMS_ID
300000053605
Created by admin on Mon Mar 31 17:47:15 GMT 2025 , Edited by admin on Mon Mar 31 17:47:15 GMT 2025
PRIMARY
Related Record Type Details
Structure of SODIUM ARSENATE, DIBASIC HEPTAHYDRATE
SOLVATE->ANHYDROUS
Related Record Type Details
Structure of ARSENATE ION
ACTIVE MOIETY
NIH
NCATS
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