IPRAZOCHROME

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H16N4O3
Molecular Weight	264.2804
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of IPRAZOCHROME

Structure Search

SMILES

CC(C)N1CC(O)C2=C\C(=N\NC(N)=O)C(=O)C=C12

InChI

InChIKey=XZKVIDLLLOUTSS-ZSOIEALJSA-N

InChI=1S/C12H16N4O3/c1-6(2)16-5-11(18)7-3-8(14-15-12(13)19)10(17)4-9(7)16/h3-4,6,11,18H,5H2,1-2H3,(H3,13,15,19)/b14-8-

HIDE SMILES / InChI

Molecular Formula	C12H16N4O3
Molecular Weight	264.2804
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7443760 | https://www.ncbi.nlm.nih.gov/pubmed/10463251 | https://www.ncbi.nlm.nih.gov/pubmed/3900979 | https://www.i-apteka.pl/product-pol-48541-DIVASCAN-tabletki.html

Iprazochrome is a serotonin antagonist both in vitro and in vivo. It is used in the prophylaxis of migraine and in the treatment of diabetic retinopathy.

CNS Activity

Approval Year

Patents

Patents

Sample Use Guides

In Vivo Use Guide

In adults, the usual dose is 1 - 2 (maximum 3) tablets of Divascan (Iprazochrome 2.5 mg) 3 times a day.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:51:40 UTC 2023` Edited by `admin` on `Sat Dec 16 17:51:40 UTC 2023`
Record UNII	903A9K181P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IPRAZOCHROME

Official Name

English

iprazochrome [INN]

Common Name

English

NSC-10065

Code

English

Iprazochrome [WHO-DD]

Common Name

English

3-HYDROXY-1-ISOPROPYL-5,6-INDOLINEDIONE 5-SEMICARBAZONE

Systematic Name

English

DIVASCAN

Brand Name

English

IPRAZOCHROME [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66885

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

WHO-ATC

N02CX03

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

WHO-VATC

QN02CX03

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

Code System Code Type Description

NSC

10065

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

PRIMARY

PUBCHEM

6381821

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

PRIMARY

ChEMBL

CHEMBL2104324

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

PRIMARY

CAS

7248-21-7

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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INN

4427

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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EPA CompTox

DTXSID70864030

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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WIKIPEDIA

IPRAZOCHROME

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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SMS_ID

100000083122

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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FDA UNII

903A9K181P

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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DRUG CENTRAL

1476

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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DRUG BANK

DB13541

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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EVMPD

SUB08277MIG

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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NCI_THESAURUS

C83834

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

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RXCUI

51486

Created by admin on Sat Dec 16 17:51:40 UTC 2023 , Edited by admin on Sat Dec 16 17:51:40 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					903A9K181P

ACTIVE MOIETY