PARCONAZOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H16Cl2N2O3
Molecular Weight	367.227
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C(Cl)=C1)[C@]3(CN2C=CN=C2)OC[C@@H](COCC#C)O3

InChI

InChIKey=SWKACZZMDOWWGU-RHSMWYFYSA-N

InChI=1S/C17H16Cl2N2O3/c1-2-7-22-9-14-10-23-17(24-14,11-21-6-5-20-12-21)15-4-3-13(18)8-16(15)19/h1,3-6,8,12,14H,7,9-11H2/t14-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H16Cl2N2O3
Molecular Weight	367.227
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ema.europa.eu/en/documents/mrl-report/parconazole-summary-report-committee-veterinary-medicinal-products_en.pdf

Parconazole is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of action involves inhibition of the fungal cytochrome P450 dependent 14alpha-dimethylation of lanosterol to ergosterol.

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:19:58 GMT 2025` Edited by `admin` on `Mon Mar 31 18:19:58 GMT 2025`
Record UNII	8Z2Z19C8Z1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PARCONAZOLE

Official Name

English

CIS-1-((2-(2,4-DICHLOROPHENYL)-4-((2-PROPYNYLOXY)METHYL)-1,3-DIOXOLAN-2-YL)METHYL)IMIDAZOLE

Preferred Name

English

1H-IMIDAZOLE, 1-((2-(2,4-DICHLOROPHENYL)-4-((2-PROPYNYLOXY)METHYL)-1,3-DIOXOLAN-2-YL)METHYL)-

Systematic Name

English

parconazole [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514