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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H25NO2
Molecular Weight 311.418
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KETORFANOL

SMILES

[H][C@]12CC3=C(C(O)=CC=C3)[C@@]5(CCN1CC4CC4)CC(=O)CC[C@@]25[H]

InChI

InChIKey=ORMBBVGVPWUEMQ-QKLQHJQFSA-N
InChI=1S/C20H25NO2/c22-15-6-7-16-17-10-14-2-1-3-18(23)19(14)20(16,11-15)8-9-21(17)12-13-4-5-13/h1-3,13,16-17,23H,4-12H2/t16-,17+,20-/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H25NO2
Molecular Weight 311.418
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

KETORFANOL, a morphinan derivative, is an opioid analgesic. It showed potent antiwrithing activity in the animal assay. It was equipotent with morphine as an agonist and lacked antagonist activity up to 10 mg/kg.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
8Z0ZXE70XL
Record Status Validated (UNII)
Record Version