MILFASARTAN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H30N6O3S
Molecular Weight	554.663
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC1=C(CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4)C(=O)N(CC5=C(C=CS5)C(=O)OC)C(C)=N1

InChI

InChIKey=QVFVAKQHELFATN-UHFFFAOYSA-N

InChI=1S/C30H30N6O3S/c1-4-5-10-26-25(29(37)36(19(2)31-26)18-27-24(15-16-40-27)30(38)39-3)17-20-11-13-21(14-12-20)22-8-6-7-9-23(22)28-32-34-35-33-28/h6-9,11-16H,4-5,10,17-18H2,1-3H3,(H,32,33,34,35)

HIDE SMILES / InChI

Molecular Formula	C30H30N6O3S
Molecular Weight	554.663
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18191398 | https://adisinsight.springer.com/drugs/800002993

Milfasartan is an inhibitor of angiotensin II receptor type 1 was used in phase II clinical trial for the treatment of hypertension. However, these studies were discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:14:15 UTC 2023` Edited by `admin` on `Fri Dec 15 16:14:15 UTC 2023`
Record UNII	8UAL5421CL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MILFASARTAN

Official Name

English

milfasartan [INN]

Common Name

English

METHYL 2-((4-BUTYL-2-METHYL-6-OXO-5-(P-(O-1H-TETRAZOL-5-YLPHENYL)BENZYL)-1(6H)-PYRIMIDINYL)METHYL)-3-THIOPHENECARBOXYLATE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66930