Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C15H14O9S |
| Molecular Weight | 370.331 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@@H]1CC2=C(OS(O)(=O)=O)C=C(O)C=C2O[C@@H]1C3=CC(O)=C(O)C=C3
InChI
InChIKey=MWSSRHFQMROXGK-IUODEOHRSA-N
InChI=1S/C15H14O9S/c16-8-4-13-9(14(5-8)24-25(20,21)22)6-12(19)15(23-13)7-1-2-10(17)11(18)3-7/h1-5,12,15-19H,6H2,(H,20,21,22)/t12-,15-/m1/s1
| Molecular Formula | C15H14O9S |
| Molecular Weight | 370.331 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Absorption, metabolism, distribution and excretion of (-)-epicatechin: A review of recent findings. | 2018-06 |
|
| Cocoa flavanol metabolites activate HNF-3β, Sp1, and NFY-mediated transcription of apolipoprotein AI in human cells. | 2013-06 |
|
| Identification of O-methyl-(-)-epicatechin-O-sulphate metabolites by mass-spectrometry after O-methylation with trimethylsilyldiazomethane. | 2012-07-06 |
|
| Inhibitory effect of tannic acid sulfate and related sulfates on infectivity, cytopathic effect, and giant cell formation of human immunodeficiency virus. | 1992-12 |
Patents
Sample Use Guides
Epicatechin-5-Sulfate is patented for inclusion in food compositions intended to be used for weight loss, and treatment of diabetes. The patent suggests a concentration of at least 0.01 mg/g of the food product.
Route of Administration:
Oral
Human hepatocellular carcinoma HepG2 and human cervix adenocarcinoma HeLa cells were grown in Ham's F-12 medium supplemented with 7% fetal bovine serum at 37 deg-C in a 5% CO2 atmosphere. Cells were incubated with 10 micro-M of epicatechin sulfate for 48 hours. Cells cultures were assayed for RNA content and content of nuclear extracts. Epicatechin sulfate was found to induce ApoAI transcription through Site B.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:02:52 GMT 2025
by
admin
on
Mon Mar 31 22:02:52 GMT 2025
|
| Record UNII |
8T66C0D002
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
300000013085
Created by
admin on Mon Mar 31 22:02:52 GMT 2025 , Edited by admin on Mon Mar 31 22:02:52 GMT 2025
|
PRIMARY | |||
|
8T66C0D002
Created by
admin on Mon Mar 31 22:02:52 GMT 2025 , Edited by admin on Mon Mar 31 22:02:52 GMT 2025
|
PRIMARY | |||
|
71579119
Created by
admin on Mon Mar 31 22:02:52 GMT 2025 , Edited by admin on Mon Mar 31 22:02:52 GMT 2025
|
PRIMARY | |||
|
1194377-44-0
Created by
admin on Mon Mar 31 22:02:52 GMT 2025 , Edited by admin on Mon Mar 31 22:02:52 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE LESS ACTIVE |
