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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H14O9S
Molecular Weight 370.331
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EPICATECHIN-5-SULFATE

SMILES

O[C@@H]1CC2=C(O[C@@H]1C3=CC(O)=C(O)C=C3)C=C(O)C=C2OS(O)(=O)=O

InChI

InChIKey=MWSSRHFQMROXGK-IUODEOHRSA-N
InChI=1S/C15H14O9S/c16-8-4-13-9(14(5-8)24-25(20,21)22)6-12(19)15(23-13)7-1-2-10(17)11(18)3-7/h1-5,12,15-19H,6H2,(H,20,21,22)/t12-,15-/m1/s1

HIDE SMILES / InChI

Molecular Formula C15H14O9S
Molecular Weight 370.331
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Epicatechin-5-Sulfate is a metabolite of epicatechin. It is patented for inclusion in food formulations intended for weight loss, and treatment of diabetes.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown
Primary
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Epicatechin-5-Sulfate is patented for inclusion in food compositions intended to be used for weight loss, and treatment of diabetes. The patent suggests a concentration of at least 0.01 mg/g of the food product.
Route of Administration: Oral
In Vitro Use Guide
Human hepatocellular carcinoma HepG2 and human cervix adenocarcinoma HeLa cells were grown in Ham's F-12 medium supplemented with 7% fetal bovine serum at 37 deg-C in a 5% CO2 atmosphere. Cells were incubated with 10 micro-M of epicatechin sulfate for 48 hours. Cells cultures were assayed for RNA content and content of nuclear extracts. Epicatechin sulfate was found to induce ApoAI transcription through Site B.
Substance Class Chemical
Record UNII
8T66C0D002
Record Status Validated (UNII)
Record Version