U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2009
359
Substance Class Structurally Diverse
Created
by admin
on Fri Dec 15 22:00:20 GMT 2023
Edited
by admin
on Fri Dec 15 22:00:20 GMT 2023
Source Materials Class ORGANISM
Source Materials Type PLANT
Source Materials Parent
CAMELLIA SINENSIS WHOLE
Part LEAF
Record UNII
W2ZU1RY8B0
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
GREEN TEA LEAF
Common Name English
THEA SINENSIS [HPUS]
Common Name English
CHA YE
Common Name English
CAMELLIAE SINENSIS FOLIUM
Common Name English
CAMELLIA SINENSIS LEAF
INCI   WHO-DD  
INCI  
Official Name English
SENCHA TEA
Common Name English
Camellia sinensis leaf [WHO-DD]
Common Name English
MATCHA TEA
Common Name English
GREEN TEA [EMA HERBAL SUBSTANCE]
Common Name English
CAMELLIAE FOLIUM
Common Name English
MATCHA TEA LEAF
Common Name English
CAMELLIA SINENSIS LEAF [INCI]
Common Name English
Camellia sinensis leaf extract [WHO-DD]
Common Name English
CAMELLIAE SINENSIS NON FERMENTATUM FOLIUM [EMA HERBAL SUBSTANCE]
Common Name English
GREEN TEA [VANDF]
Common Name English
GREEN TEA LEAF EXTRACT
Common Name English
SENCHA TEA LEAF
Common Name English
GREEN TEA
EMA HERBAL SUBSTANCE   VANDF  
Common Name English
Classification Tree Code System Code
LIVERTOX NBK547925
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
EMA ASSESSMENT REPORTS CAMELLIA (FINALIZED)
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
LIVERTOX NBK548570
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
NCI_THESAURUS C106105
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
DSLD 1173 (Number of products:3408)
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
Code System Code Type Description
RXCUI
283567
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
FDA UNII
W2ZU1RY8B0
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
EVMPD
SUB15458MIG
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
NCI_THESAURUS
C67048
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY NCIT
EVMPD
SUB32750
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
DAILYMED
W2ZU1RY8B0
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
DRUG BANK
DB14307
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
LACTMED
Green Tea
Created by admin on Fri Dec 15 22:00:20 GMT 2023 , Edited by admin on Fri Dec 15 22:00:20 GMT 2023
PRIMARY
Related Record Type Details
Structure of EPIGALLOCATECHIN GALLATE
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
CAMELLIA SINENSIS LEAF POWDER
SUB_CONCEPT->SUBSTANCE
Structure of GALLOCATECHIN
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of EPICATECHIN
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
IN-VITRO
TEA EXTRACT
SUB_CONCEPT->SUBSTANCE
Structure of EPIGALLOCATECHIN GALLATE
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
IN-VITRO
Structure of EPIGALLOCATECHIN
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
IN-VITRO
Structure of EPICATECHIN GALLATE
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
IN-VITRO
Structure of THEANINE
CONSTITUENT ALWAYS PRESENT -> PARENT
Structure of CIANIDANOL
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
IN-VITRO
Structure of GALLOCATECHIN GALLATE
CONSTITUENT ALWAYS PRESENT -> PARENT
Related Record Type Details
Structure of 4'-METHYL-EPIGALLOCATECHIN-7-GLUCURONIDE
METABOLITE -> PARENT
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Structure of (-)-5-(3',4'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE
METABOLITE LESS ACTIVE -> PARENT
ABTS radical scavenging analysis; Unit: Trolox equivalent value
IN-VITRO
Structure of EPIGALLOCATECHIN-3'-GLUCURONIDE
METABOLITE ACTIVE -> PARENT
EC50 of DPPH radical scavenging activities (molar ration of catechin/DPPH)
IN-VITRO
Structure of EPIGALLOCATECHIN-3'-GLUCURONIDE
METABOLITE ACTIVE -> PARENT
Inhibition of arachidonic acid release from HT-29 cells; Unit: percent of control: percent of control at 2mcM
IN-VITRO
Structure of 4''-METHYLEPIGALLOCATECHIN GALLATE
METABOLITE -> PARENT
IN-VIVO
PLASMA
Structure of (-)-5-(3',4',5'-TRIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-3'-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of EPICATECHIN-4'-SULFATE
METABOLITE LESS ACTIVE -> PARENT
FRAP (ferric reducing ability of plasma) assay; Unit: TEAC (Trolox equivalent antioxidant capacity)- mM-Trolox equivalent/mM; epicatechin was 1.34
IN-VITRO
Structure of 4'-METHYLEPICATECHIN-7-SULFATE
METABOLITE -> PARENT
IN-VIVO
PLASMA; URINE
Structure of (-)-5-(3',4',5'-TRIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-4'-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of (-)-5-(3',4'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-3'-O-METHYL-4'-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of EPIGALLOCATECHIN-7-GLUCURONIDE
METABOLITE ACTIVE -> PARENT
EC50 of DPPH radical scavenging activities (molar ration of catechin/DPPH)
IN-VITRO
Structure of (-)-5-(3',4'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE
METABOLITE LESS ACTIVE -> PARENT
IN-VIVO
URINE
Structure of PYROGALLOL-2-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 4-HYDROXY-5-(3',5'-DIHYDROXYPHENYL)-.GAMMA.-VALERIC ACID-3'-O-SULFATE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 4'-METHYL-EPIGALLOCATECHIN-3'-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of EPICATECHIN-7-GLUCURONIDE
METABOLITE ACTIVE -> PARENT
Superoxide Dismutase Assay (SOD kit-WST); IC50 was lower than that of epicatechin.
IN-VITRO
IC50
Structure of 3'-METHYLEPICATECHIN-4'-SULFATE
METABOLITE -> PARENT
IN-VIVO
PLASMA; URINE
Structure of 4'-METHYLEPICATECHIN
METABOLITE LESS ACTIVE -> PARENT
ORAC (oxygen radical absorbance capacity) assay; Unit: mol-Trolox equivalent/mol
IN-VITRO
Structure of (-)-5-(3',5'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE
METABOLITE LESS ACTIVE -> PARENT
ABTS radical scavenging analysis; Unit: Trolox equivalent value
IN-VITRO
Structure of (-)-5-(3',4'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-4'-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of EPICATECHIN-3'-GLUCURONIDE
METABOLITE LESS ACTIVE -> PARENT
Antioxidative activities on plasma TBARS (thiobarbituric reactive substances) production at 42.9mcM; Unit: percent of inhibition
IN-VITRO
Structure of INDOLE-3-ACETIC ACID-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 3-Hydroxy-5-[[(2R)-tetrahydro-5-oxo-2-furanyl]methyl]phenyl β-D-glucopyranosiduronic acid
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 4'-METHYLEPICATECHIN-3'-SULFATE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of EPICATECHIN-5-SULFATE
METABOLITE LESS ACTIVE -> PARENT
FRAP (ferric reducing ability of plasma) assay; Unit: TEAC (Trolox equivalent antioxidant capacity)- mM-Trolox equivalent/mM; epicatechin was 1.34
IN-VITRO
Structure of HIPPURIC ACID
METABOLITE INACTIVE -> PARENT
IN-VIVO
URINE
Structure of 4'-METHYLEPICATECHIN-3'-GLUCURONIDE
METABOLITE INACTIVE -> PARENT
IN-VITRO
Structure of 4',4''-DIMETHYLEPIGALLOCATECHIN GALLATE
METABOLITE LESS ACTIVE -> PARENT
Ferric reducing antioxidant parameter (FRAP) assay; Unit: mcM trolox equivalent)
IN-VITRO
Structure of 2-Hydroxy-5-[[(2R)-tetrahydro-5-oxo-2-furanyl]methyl]phenyl β-D-glucopyranosiduronic acid
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 4'-METHYL-EPIGALLOCATECHIN-3'-SULFATE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 4'-METHYL-EPIGALLOCATECHIN
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of (-)-5-(3',4',5'-TRIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 4'-METHYLEPICATECHIN
METABOLITE LESS ACTIVE -> PARENT
FRAP (ferric reducing ability power) assay; Unit: Trolox equivalent
IN-VITRO
Structure of 4'-METHYLEPICATECHIN-5-SULFATE
METABOLITE -> PARENT
IN-VIVO
PLASMA; URINE
Structure of (-)-5-(3',5'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE
METABOLITE LESS ACTIVE -> PARENT
IN-VIVO
URINE
Structure of 3'-METHYLEPICATECHIN
METABOLITE LESS ACTIVE -> PARENT
ORAC (oxygen radical absorbance capacity) assay; Unit: mol-Trolox equivalent (TE)/mol
IN-VITRO
Structure of (-)-5-(3'-HYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-3'-O-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of (-)-5-(3',4',5'-TRIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-3'-O-SULFATE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of EPICATECHIN-4'-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
PLASMA; URINE
Structure of 4'-METHYLEPICATECHIN-7-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
PLASMA
Structure of EPICATECHIN-3'-SULFATE
METABOLITE LESS ACTIVE -> PARENT
FRAP (ferric reducing ability of plasma) assay; Unit: Trolox equivalent antioxidant capacity (TEAC)- mM-Trolox equivalent/mM; epicatechin was 1.34
IN-VITRO
Structure of 4-HYDROXY-3-METHOXYBENZOYLGLYCINE
METABOLITE INACTIVE -> PARENT
IN-VIVO
URINE
Structure of EPIGALLOCATECHIN-7-GLUCURONIDE
METABOLITE ACTIVE -> PARENT
Inhibition of arachidonic acid release from HT-29 cells; Unit: percent of control at 10mcM
IN-VITRO
Structure of (-)-5-(4'-HYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-4'-GLUCURONIDE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of PYROGALLOL-2-O-SULFATE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 3'-METHYLEPICATECHIN
METABOLITE LESS ACTIVE -> PARENT
FRAP (ferric reducing power) assay; Unit: Trolox equivalent
IN-VITRO
Structure of 3'-METHYLEPICATECHIN-5-SULFATE
METABOLITE -> PARENT
IN-VIVO
PLASMA; URINE
Structure of (-)-5-(3',5'-DIHYDROXYPHENYL)-.GAMMA.-VALEROLACTONE-3'-O-SULFATE
METABOLITE -> PARENT
IN-VIVO
URINE
Structure of 3'-METHYLEPICATECHIN-7-SULFATE
METABOLITE -> PARENT
IN-VIVO
FECAL; URINE
Related Record Type Details
GREEN TEA LEAF
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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National Center for Advancing Translational Sciences (NCATS),
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