IDECABTAGENE VICLEUCEL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Tue Apr 01 23:36:52 GMT 2025` Edited by `admin` on `Tue Apr 01 23:36:52 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	AUTOLOGOUS HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	blood
Fraction Material Type	cell
Fraction Name	t-cells
Record UNII	8PX1X7UG4D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ABECMA

Preferred Name

English

IDECABTAGENE VICLEUCEL

Official Name

English

HUMAN CULTURE EXPANDED GENETICALLY MODIFIED AUTOLOGOUS T CELLS FOR CELL-BASED GENE THERAPY. CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE SELF-INACTIVATING (SIN) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) B

Common Name

English

idecabtagene vicleucel [INN]

Common Name

English

IDE-CEL

Common Name

English

Idecabtagene vicleucel [WHO-DD]

Common Name

English

IDECABTAGENE VICLEUCEL [USAN]

Common Name

English

BB2121

Code

English

ANTI-BCMA CAR T CELL

Common Name

English

BB-2121

Code

English

Code System Code Type Description

NCI_THESAURUS

C117729

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

PRIMARY

USAN

GH-44

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

PRIMARY

RXCUI

2536430

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

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SMS_ID

100000183404

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

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DAILYMED

8PX1X7UG4D

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

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INN

10906

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

PRIMARY

FDA UNII

8PX1X7UG4D

Created by admin on Tue Apr 01 23:36:52 GMT 2025 , Edited by admin on Tue Apr 01 23:36:52 GMT 2025

PRIMARY

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					PK6VHJAIBD

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17

TARGET->CYTOTOXIC T-CELL

Amount:

Related Record Type Details


					8PX1X7UG4D

IDECABTAGENE VICLEUCEL

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
CULTURED	TRANSFECTION	RETROVIRAL TRANSFECTION		ANTI-BCMA02 CAR LENTIVIRAL VECTOR	24U06E3FHJ

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
VECTOR EXPRESSED PROTEIN					IDECABTAGENE VICLEUCEL CAR T RECEPTOR	H4ON8SV8LK
INSERTED GENE EXPRESSION VECTOR					ANTI-BCMA02 CAR LENTIVIRAL VECTOR CDNA	D2AT57OS3D