CARBARSONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9AsN2O4
Molecular Weight	260.079
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NC(=O)NC1=CC=C(C=C1)[As](O)(O)=O

InChI

InChIKey=WWXBHTZSYYGCSG-UHFFFAOYSA-N

InChI=1S/C7H9AsN2O4/c9-7(11)10-6-3-1-5(2-4-6)8(12,13)14/h1-4H,(H3,9,10,11)(H2,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C7H9AsN2O4
Molecular Weight	260.079
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Carbarsone is an antiambeic, antihistomonal drug effective in controlling and preventing blackhead disease in turkeys (a disease caused by a protozoan parasite Histomonas meleagridis). Carbarsone was approved by FDA, however, it has not been marketed in the USA scince 1996.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Blackhead disease 1	Preventing		Approved 8,429	CARB-O-SEP

PubMed

Show entries

Title	Date	PubMed
The mechanism of coprosterol formation in vivo: 2. Its inhibition by succinyl sulphathiazole and by carbarsone.	1943	16747699
Less commonly recognized clinical features of amebiasis.	1952 Apr	14925826
Balantidial dysentery.	1953 Sep	13082481
Trichomonas urethritis in males.	1955 Dec	13270111
Virulence Of Entamoeba Histolytica According To The Strains In Korea: III. Amebicial Response Of Antiamoebic Agents On Several Strains Of Entamoeba Histolytica In Vitro.	1969 Dec	12913525

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Patents

Sample Use Guides

In Vivo Use Guide

227 to 340.5 (0.025 to 0.0375 percent) grams per ton feed.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical
Record UNII	8PK70TXE1T
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

CARBARSONE

Official Name

English

AMEBAN

Common Name

English

carbarsone [INN]

Common Name

English

CARBARSONE [GREEN BOOK]

Common Name

English

CARBARSON

Common Name

English

Showing 1 to 5 of 11 entries

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Classification Tree

Code System

Code

Antiparasitic Agent

NCI_THESAURUS

C277

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Code System

Code

Type

Description

MERCK INDEX

m3057

PRIMARY

Merck Index

PUBCHEM

8480

PRIMARY

CAS

121-59-5

PRIMARY

NSC

32868

PRIMARY

DRUG CENTRAL

3065

PRIMARY

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Related Record

Type

Details


					8PK70TXE1T

CARBARSONE

ACTIVE MOIETY

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