ALLOBARBITAL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H12N2O3
Molecular Weight	208.2139
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C=CCC1(CC=C)C(=O)NC(=O)NC1=O

InChI

InChIKey=FDQGNLOWMMVRQL-UHFFFAOYSA-N

InChI=1S/C10H12N2O3/c1-3-5-10(6-4-2)7(13)11-9(15)12-8(10)14/h3-4H,1-2,5-6H2,(H2,11,12,13,14,15)

HIDE SMILES / InChI

Molecular Formula	C10H12N2O3
Molecular Weight	208.2139
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=4yaGePenGKgC&printsec=frontcover&hl=ru#v=onepage&q&f=false | https://www.ncbi.nlm.nih.gov/pubmed/35131 | https://www.ncbi.nlm.nih.gov/pubmed/4335127 | https://www.ncbi.nlm.nih.gov/pubmed/3439474

Allobarbital (5,5-diallylbarbituric acid) is a medium to long-acting barbiturate. It is under international control according to the UN Convention on Psychotropic Substances (Schedule IV). It is used as a sedative and hypnotic and in combination with acetaminophen and codeine as an analgesic. Allobarbital exerts anticonvulsive activity through GABA-ergic mechanisms. Sulfuric derivatives of allobarbital may exert anti-inflammatory activity.

CNS Activity

Approval Year

PubMed

Title	Date	PubMed
Improved solid-phase extraction method for systematic toxicological analysis in biological fluids.	2001 Mar	11300506
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.	2001 Nov	11792017
Application of atmospheric pressure chemical ionisation mass spectrometry in the analysis of barbiturates by high-speed analytical countercurrent chromatography.	2003	12845581
[Studies on the structure-activity relationship of allyl substituted oxopyrimidines searching for the novel antagonist or agonist of barbiturates to the sleep mechanism based on the uridine receptor theory--barbituric acid to uridine (part I)].	2005 Jan	15635282
Rostral ventrolateral medullary but not medullary lateral tegmental field neurons mediate sympatho-sympathetic reflexes in cats.	2010 Nov	20811005

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:12:14 UTC 2023` Edited by `admin` on `Fri Dec 15 15:12:14 UTC 2023`
Record UNII	8NT43GG2HA
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ALLOBARBITAL

Official Name

English

NSC-9324

Code

English

ALLOBARBITAL [MI]

Common Name

English

allobarbital [INN]

Common Name

English

ALLOBARBITAL [MART.]

Common Name

English

2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5,5-DI-2-PROPENYL-

Systematic Name

English

Allobarbital [WHO-DD]

Common Name

English

5,5-Diallylbarbituric acid

Systematic Name

English

ALLOBARBITAL [USAN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

N05CA21