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Details

Stereochemistry ACHIRAL
Molecular Formula C10H12N2O3
Molecular Weight 208.2139
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALLOBARBITAL

SMILES

C=CCC1(CC=C)C(=O)NC(=O)NC1=O

InChI

InChIKey=FDQGNLOWMMVRQL-UHFFFAOYSA-N
InChI=1S/C10H12N2O3/c1-3-5-10(6-4-2)7(13)11-9(15)12-8(10)14/h3-4H,1-2,5-6H2,(H2,11,12,13,14,15)

HIDE SMILES / InChI
Molecular Formula C10H12N2O3
Molecular Weight 208.2139
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Allobarbital (5,5-diallylbarbituric acid) is a medium to long-acting barbiturate. It is under international control according to the UN Convention on Psychotropic Substances (Schedule IV). It is used as a sedative and hypnotic and in combination with acetaminophen and codeine as an analgesic. Allobarbital exerts anticonvulsive activity through GABA-ergic mechanisms. Sulfuric derivatives of allobarbital may exert anti-inflammatory activity.

CNS Activity

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Rostral ventrolateral medullary but not medullary lateral tegmental field neurons mediate sympatho-sympathetic reflexes in cats.
2010-11
[Studies on the structure-activity relationship of allyl substituted oxopyrimidines searching for the novel antagonist or agonist of barbiturates to the sleep mechanism based on the uridine receptor theory--barbituric acid to uridine (part I)].
2005-01
Application of atmospheric pressure chemical ionisation mass spectrometry in the analysis of barbiturates by high-speed analytical countercurrent chromatography.
2003
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.
2001-11
The hepatic extraction of plasma free amino acids and response to hepatic portal venous infusion of methionine sources in anesthetized SCWL males (Gallus domesticus).
2001-09
Improved solid-phase extraction method for systematic toxicological analysis in biological fluids.
2001-03
Patents

Patents

04232009
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:50:02 GMT 2025
Edited
by admin
on Mon Mar 31 17:50:02 GMT 2025
Record UNII
8NT43GG2HA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-9324
Preferred Name English
ALLOBARBITAL
INN   MART.   MI   USAN   WHO-DD  
USAN   INN  
Official Name English
ALLOBARBITAL [MI]
Common Name English
allobarbital [INN]
Common Name English
ALLOBARBITAL [MART.]
Common Name English
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5,5-DI-2-PROPENYL-
Systematic Name English
ALLOBARBITONE
Common Name English
Allobarbital [WHO-DD]
Common Name English
5,5-Diallylbarbituric acid
Systematic Name English
ALLOBARBITAL [USAN]
Common Name English
Classification Tree Code System Code
WHO-ATC N05CA21
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
NCI_THESAURUS C67084
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
WHO-VATC QN05CA21
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
Code System Code Type Description
MERCK INDEX
m1525
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY Merck Index
RXCUI
516
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY RxNorm
PUBCHEM
5842
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
200-140-4
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
EVMPD
SUB05334MIG
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
FDA UNII
8NT43GG2HA
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
ChEMBL
CHEMBL267719
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
EPA CompTox
DTXSID9022572
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
WIKIPEDIA
ALLOBARBITAL
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
SMS_ID
100000092760
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
INN
2266
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
NSC
9324
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
CAS
52-43-7
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
MESH
C084828
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
NCI_THESAURUS
C76522
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
WIKIPEDIA
Allobarbital
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
DRUG CENTRAL
122
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
DRUG BANK
DB13577
Created by admin on Mon Mar 31 17:50:02 GMT 2025 , Edited by admin on Mon Mar 31 17:50:02 GMT 2025
PRIMARY
Related Record Type Details
Structure of ALLOBARBITAL
ACTIVE MOIETY
NIH
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