| Stereochemistry | RACEMIC |
| Molecular Formula | C6H8FN3O3 |
| Molecular Weight | 188.147 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(C[18F])CN1C=CN=C1[N+]([O-])=O
InChI
InChIKey=HIIJZYSUEJYLMX-JZRMKITLSA-N
InChI=1S/C6H8FN3O3/c7-3-5(11)4-9-2-1-8-6(9)10(12)13/h1-2,5,11H,3-4H2/i7-1
| Molecular Formula | C6H8FN3O3 |
| Molecular Weight | 188.147 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Fluoromisonidazole F-18 ([F-18] FMISO) is used as a positron emission tomography (PET) radiotracer for imaging. It is generated by labeling fluoromisonidazole with fluorine-18. It is the most widely used nitroimidazole imaging agent for use as a non-invasive way to localize and quantify hypoxia. [18F] decays by positron emission. FMISO binds covalently to cellular molecules at rates that are inversely proportional to intracellular oxygen concentration. In hypoxic cells, FMISO is trapped, which is the basis for the use of this tracer to measure hypoxia.
