FLUNOPROST

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H29FO5
Molecular Weight	392.4611
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O[C@@H](COC1=CC=CC=C1)\C=C\[C@H]2[C@H](O)C[C@@H](F)[C@@H]2C\C=C/CCCC(O)=O

InChI

InChIKey=KDVWQPQZDKHFOC-PTRXCMEYSA-N

InChI=1S/C22H29FO5/c23-20-14-21(25)19(18(20)10-6-1-2-7-11-22(26)27)13-12-16(24)15-28-17-8-4-3-5-9-17/h1,3-6,8-9,12-13,16,18-21,24-25H,2,7,10-11,14-15H2,(H,26,27)/b6-1-,13-12+/t16-,18-,19-,20-,21-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H29FO5
Molecular Weight	392.4611
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	2
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1696744 | https://www.ncbi.nlm.nih.gov/pubmed/1711769

Flunoprost is a prostaglandin analog. Flunoprost has been used to treat platelet-activating factor-induced shock and to prolong skin allograft survival in mouse models.

Approval Year

PubMed

Title	Date	PubMed
Influence of some prostaglandins and prostaglandin analogues on PAF-induced shock in mice.	1990 Jun	1696744
Influence of some prostaglandin-analogues on mouse skin allograft survival compared to dexamethasone. Possible role of thromboxane.	1991 Jan	1711769

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:51:57 UTC 2023` Edited by `admin` on `Sat Dec 16 17:51:57 UTC 2023`
Record UNII	8MF6L4447J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUNOPROST

Official Name

English

(Z)-7-((1R,2R,3R,5R)-5-FLUORO-3-HYDROXY-2-((E)-(3R)-3-HYDROXY-4-PHENOXY-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOIC ACID

Systematic Name

English

flunoprost [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78568