Pegunigalsidase Alfa

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:29:15 GMT 2025` Edited by `admin` on `Wed Apr 02 02:29:15 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	8M7V7Q6537
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

PRX-102

Preferred Name

English

Pegunigalsidase Alfa

Official Name

English

PEGUNIGALSIDASE ALFA [USAN]

Common Name

English

Pegunigalsidase alfa [WHO-DD]

Common Name

English

pegunigalsidase alfa [INN]

Common Name

English

POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-(2-((3-CARBOXY-1-OXOPROPYL)AMINO)ETHYL)-.OMEGA.-(2-((3-CARBOXY-1-OXOPROPYL)AMINO)ETHOXY)-, AMIDE WITH .ALPHA.-GALACTOSIDASE (GLYCYL,398A-SERINE,398B-GLUTAMIC ACID,398C-LYSINE,398D-ASPARTIC ACID,398E-GLUTAMIC ACID,398F-LE

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/17/1953

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

FDA ORPHAN DRUG

162302

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

Code System Code Type Description

CAS

1644392-61-9

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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DRUG BANK

DB14992

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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DAILYMED

8M7V7Q6537

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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USAN

GH-87

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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PUBCHEM

121488171

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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FDA UNII

8M7V7Q6537

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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INN

10304

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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NCI_THESAURUS

C175187

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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SMS_ID

100000174563

Created by admin on Wed Apr 02 02:29:15 GMT 2025 , Edited by admin on Wed Apr 02 02:29:15 GMT 2025

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From	To
1_22	1_64
1_26	1_33
1_112	1_142
1_172	1_193
1_348	1_352
2_22	2_64
2_26	2_33
2_112	2_142
2_172	2_193
2_348	2_352

Glycosylation Type

PLANT

Glycosylation Link Type	Site
N	1_109
N	1_162
N	1_185
N	1_378
N	2_109
N	2_162
N	2_185
N	2_378

Related Record Type Details

Pegunigalsidase Alfa-IWXJ

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					8M7V7Q6537

Pegunigalsidase Alfa

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION			G	Amount:	GLYCINYL-SUCCIMIDE-PEG-45-SUCCINIC ACID	9E2T9M1G4Y
AMINO ACID SUBSTITUTION			K		N6-LYSYL-SUCCIMIDE-PEG-45-SUCCIMIDE GLYCINE	B85M4AQW5F
AMINO ACID SUBSTITUTION			K		PEG-45 BIS(N6-LYSYL-SUCCIMIDE)	R350G7L1JR
AMINO ACID SUBSTITUTION			K	Amount:	N6-LYSYL-SUCCIMIDE-PEG-45-SUCCINIC ACID	NDD0M3CW3D
AMINO ACID SUBSTITUTION			G		N6-LYSYL-SUCCIMIDE-PEG-45-SUCCIMIDE GLYCINE	B85M4AQW5F
AMINO ACID SUBSTITUTION			G		PEG-45 BIS(N6-LYSYL-SUCCIMIDE)	R350G7L1JR

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL